ArticleJournal of clinical neurophysiology : official publication of the American Electroencephalographic Society2012
Seizure localization using broadband EEG: comparison of conventional frequency activity, high-frequency oscillations, and infraslow activity.
Article in Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- The role of high-frequency oscillations in epilepsy surgery planning.The Cochrane database of systematic reviews · 2017Pooled it
- The role of high-frequency oscillations in epilepsy surgery planning.The Cochrane database of systematic reviews · 2014Pooled it
- Predicting seizure onset zones from interictal intracranial EEG using functional connectivity and machine learning.Scientific reports · 2025Article
- A Review of EEG-based Localization of Epileptic Seizure Foci: Common Points with Multimodal Fusion of Brain Data.Journal of medical signals and sensors · 2024Review
- Digital reconstruction of infraslow activity in human intracranial ictal recordings using a deconvolution-based inverse filter.Scientific reports · 2022Article
- High-Frequency Oscillations and Epileptogenic Network.Current neuropharmacology · 2022Article
- Ictal direct current shifts contribute to defining the core ictal focus in epilepsy surgery.Brain communications · 2022Article
- Interictal localization of the epileptogenic zone: Utilizing the observed resonance behavior in the spectral band of surrounding inhibition.Frontiers in neuroscience · 2022Article
- Phase-amplitude coupling between infraslow and high-frequency activities well discriminates between the preictal and interictal states.Scientific reports · 2021Article
- Direct Cortical Stimulation to Probe the Ictogenicity of the Epileptogenic Nodes in Temporal Lobe Epilepsy.Frontiers in neurology · 2021Article
- Coupling between infraslow activities and high-frequency oscillations precedes seizure onset.Epilepsia open · 2020Article
- High Frequency Oscillations in Epilepsy: Detection Methods and Considerations in Clinical Application.Journal of epilepsy research · 2019Review
- Toward a Mechanistic Understanding of Epileptic Networks.Current neurology and neuroscience reports · 2016Review
- Advances of Intracranial Electroencephalography in Localizing the Epileptogenic Zone.Neuroscience bulletin · 2016Review
- The ictal wavefront is the spatiotemporal source of discharges during spontaneous human seizures.Nature communications · 2016Article
- Interictal high-frequency oscillations (HFOs) as predictors of high frequency and conventional seizure onset zones.Epileptic disorders : international epilepsy journal with videotape · 2015Article
- High frequency oscillations and infraslow activity in epilepsy.Annals of Indian Academy of Neurology · 2014Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
In neocortical epilepsy, we showed that the seizure onset defined by ictal high-frequency oscillations (HFO: ≥ 70 Hz) with subsequent evolution into slower frequency activity (i.e., HFOs+) was smaller in spatial distribution than that defined by conventional frequency activity (1-70 Hz), and that resection of HFO+ areas resulted in favorable seizure outcome. This study further investigates ictal broadband EEG in the same cohort of patients by examining the infraslow activity, including ictal baseline ("direct current") shifts (IBS) and peri-ictal infraslow activity (0.02 to 0.2 Hz). The seizure onset zone had been defined and resected based on HFO+ by a prospectively defined protocol. We reviewed 11 representative seizures from 6 patients by visual and spectral analyses using appropriate filters and timescales. The HFO seizure onset, in the high gamma or ripple frequency, preceded or followed the IBS closely (<300 ms). The IBS were negative or positive, ∼1 mV in amplitude and 2 to 3 seconds long. Although the HFO+ were always ipsilateral to the surgical hemisphere, the IBS could be ipsilateral or contralateral. Compared with conventional frequency activity, the HFO+ and IBS were significantly smaller in spatial distribution and likely to be concordant. The peri-ictal infraslow activity consisted of distinct periodic or rhythmic (0.12 to 0.16 Hz) patterns, poorly concordant with IBS or HFO+. Although not statistically significant, better seizure outcome tended to correlate with smaller seizure onset zones and more complete resection of the HFO+ and IBS contacts. We conclude that IBS, like HFO+, define a smaller seizure onset zone and probably a more accurate epileptogenic zone in neocortical epilepsy.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.