Evidence map›Paper›PMID 22854596›Full record

ArticleChimerism

Chimerism in women with end stage renal diseases: Who's who?

Laetitia Albano, Justyna M Rak, Doua F Azzouz, Elisabeth Cassuto-Viguier, Jean Gugenheim, Nathalie C Lambert

Open access · bronzeAbstract read
In one paragraph

Article in Chimerism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 87% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Laetitia AlbanoUMC Transplantation Rénale, Hôpital Pasteur, Centre Hospitalo-Universitaire de Nice, Nice, France.
Justyna M Rak
Doua F Azzouz
Elisabeth Cassuto-Viguier
Jean Gugenheim
Nathalie C Lambert
OZ Biosciences (France) · FRCentre d’Immunologie de Marseille-Luminy · FRCentre Hospitalier Universitaire de Nice · FRHôpital Pasteur · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many sources of foreign or semi foreign cells, known as microchimerism (Mc), can be found in healthy individuals. We have recently shown in women with end stage renal disease (ESRD) that Mc frequencies and levels are exacerbated prior to kidney transplantation. Is Mc arising from pregnancy a protective factor for renal diseases explaining lower incidence in women? Is Mc helpful in slowing down disease progression? However, natural Mc is not the only actor as post blood transfusion Mc is also found at high levels in women with ESRD. The difficulty is therefore to distinguish the different types of Mc and this is made even more complicated when the recipient receives a potentially chimeric organ. What part does each source of chimerism play in disease and transplant fate, and can one decipher each role knowing that one chimerism may hide another?

Indexed as

ChimerismBlood TransfusionFemaleGraft RejectionHLA AntigensHumansKidney Failure, ChronicKidney TransplantationPregnancyTissue DonorsHLA Antigens

Identifiers

PMID22854596
PMCPMC3442814
OpenAlexW2078047325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.