Evidence map›Paper›PMID 22854400›Full record

Trial reportThe American journal of clinical nutrition2012

Caloric compensation and eating in the absence of hunger in 5- to 12-y-old weight-discordant siblings.

Tanja V E Kral, David B Allison, Leann L Birch, Virginia A Stallings, Reneé H Moore, Myles S Faith

Open access · bronzeAbstract readClinical TrialControlled Clinical Trial
In one paragraph

Trial report in The American journal of clinical nutrition, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed, 5 pooled it
6.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed, 5 syntheses or guidelines pooled it, 115 citations in OpenAlex.

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4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Tanja V E KralDepartment of Biobehavioral Health Sciences, University of Pennsylvania School of Nursing and Perelman School of Medicine, Philadelphia, PA 19104, USA. tkral@nursing.upenn.edu
David B Allison
Leann L Birch
Virginia A Stallings
Reneé H Moore
Myles S Faith
California University of Pennsylvania · USPennsylvania State University · USUniversity of Alabama at Birmingham · USUniversity of Pennsylvania · US

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI James O Hill · 2000 to 2026
$31.9M
Eating Behaviors Among Weight-Discordant SiblingsK01DK078601 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI KRAL, TANJA V.E. · 2008 to 2012
$743k
NIDDK NIH HHS K01DK078601NIDDK NIH HHS P30 DK056336
6 · The paper itself

Abstract

backgroundAn impaired ability to compensate for calories and increased eating in the absence of hunger (EAH) has been associated with increased energy intake and weight gain in unrelated children.

objectiveThe aims of this study were to compare caloric compensation [the percentage compensation index (%COMPX)] and EAH in weight-discordant siblings aged 5-12 y.

designIn a crossover, behavioral genetics design, 47 same-sex sibling pairs (53% female, 55% full siblings) were served dinner once a week for 3 wk. Across conditions, siblings were served the same dinner, but 25 min before dinner, they either consumed in full or did not consume 1 of 2 preloads that varied in energy density (ED; 0.57 or 0.97 kcal/g). On the day when no preload was consumed, EAH was assessed after dinner and defined as the number of calories consumed from snacks.

resultsOverweight/obese siblings undercompensated [%COMPX: -48.8 ± 56.3 (mean ± SEM)] and therefore overate after the high-ED preload, whereas normal-weight siblings showed accurate compensation (%COMPX: 101.3 ± 51.9; P = 0.03). Furthermore, overweight/obese siblings consumed 34% more calories (93 kcal) in the absence of hunger than did normal-weight siblings (P = 0.01). Within-pair resemblances for %COMPX and EAH were stronger for full siblings (P < 0.049) than for half siblings (P > 0.23).

conclusionsAn impaired ability to regulate short-term energy intake, which includes incomplete adjustment for calorie differences in a preload and eating when satiated, may represent a behavioral phenotype for obesity in children. Future studies should test whether teaching children to focus on internal satiety cues may prevent at-risk children from overeating.

Indexed as

Appetite RegulationChild BehaviorEnergy IntakeSiblingsAdiposityChildChild DevelopmentChild, PreschoolCross-Over StudiesFast FoodsFemaleFood PreferencesHumansHyperphagiaMaleObesity

Identifiers

PMID22854400
PMCPMC3417216
OpenAlexW2134904313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.