ArticleBiophysical journal2012
What are the oxidation states of manganese required to catalyze photosynthetic water oxidation?
Article in Biophysical journal, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed.
- Electronic Structure of the SACS physical chemistry Au · 2025Article
- The Low Oxidation State Paradigm is More Consistent with XFEL Observations of the S₃ → [S₄] → S₀ Transition in Photosystem II.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Excess manganese increases photosynthetic activity via enhanced reducing center and antenna plasticity in Chlorella vulgaris.Scientific reports · 2023Article
- Does Serial Femtosecond Crystallography Depict State-Specific Catalytic Intermediates of the Oxygen-Evolving Complex?Journal of the American Chemical Society · 2023Article
- Structural insights into photosystem II assembly.Nature plants · 2021Article
- Assessment of the manganese cluster's oxidation state via photoactivation of photosystem II microcrystals.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
- Water oxidation in photosystem II.Photosynthesis research · 2019Review
- Natural isoforms of the Photosystem II D1 subunit differ in photoassembly efficiency of the water-oxidizing complex.Photosynthesis research · 2016Article
- Proton Matrix ENDOR Studies on Ca2+-depleted and Sr2+-substituted Manganese Cluster in Photosystem II.The Journal of biological chemistry · 2015Article
- Partially Oxidized Sub-10 nm MnO Nanocrystals with High Activity for Water Oxidation Catalysis.Scientific reports · 2015Article
- Rate and mechanism of the photoreduction of birnessite (MnO2) nanosheets.Proceedings of the National Academy of Sciences of the United States of America · 2015Article
- Metal oxidation states in biological water splitting.Chemical science · 2015Article
- Substrate-water exchange in photosystem II is arrested before dioxygen formation.Nature communications · 2014Article
- Mn4Ca cluster in photosynthesis: where and how water is oxidized to dioxygen.Chemical reviews · 2014Review
- Role of Oxido Incorporation and Ligand Lability in Expanding Redox Accessibility of Structurally Related MnChemical science · 2013Article
- Electronic structural changes of Mn in the oxygen-evolving complex of photosystem II during the catalytic cycle.Inorganic chemistry · 2013Article
- From natural to artificial photosynthesis.Journal of the Royal Society, Interface · 2013Article
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5 authors.
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Abstract
Photosynthetic O(2) production from water is catalyzed by a cluster of four manganese ions and a tyrosine residue that comprise the redox-active components of the water-oxidizing complex (WOC) of photosystem II (PSII) in all known oxygenic phototrophs. Knowledge of the oxidation states is indispensable for understanding the fundamental principles of catalysis by PSII and the catalytic mechanism of the WOC. Previous spectroscopic studies and redox titrations predicted the net oxidation state of the S(0) state to be (Mn(III))(3)Mn(IV). We have refined a previously developed photoassembly procedure that directly determines the number of oxidizing equivalents needed to assemble the Mn(4)Ca core of WOC during photoassembly, starting from free Mn(II) and the Mn-depleted apo-WOC complex. This experiment entails counting the number of light flashes required to produce the first O(2) molecules during photoassembly. Unlike spectroscopic methods, this process does not require reference to synthetic model complexes. We find the number of photoassembly intermediates required to reach the lowest oxidation state of the WOC, S(0), to be three, indicating a net oxidation state three equivalents above four Mn(II), formally (Mn(III))(3)Mn(II), whereas the O(2) releasing state, S(4), corresponds formally to (Mn(IV))(3)Mn(III). The results from this study have major implications for proposed mechanisms of photosynthetic water oxidation.
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