ReviewNutrition research reviews2012
Nutrition and the psychoneuroimmunology of postpartum depression.
Review in Nutrition research reviews, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- The role of diet and nutritional supplementation in perinatal depression: a systematic review.Maternal & child nutrition · 2017Pooled it
- Maternal mood, anxiety and mental health functioning after combined myo-inositol, probiotics, micronutrient supplementation from preconception: Findings from the NiPPeR RCT.Psychiatry research · 2024Trial
- Effects of vitamin D on insulin resistance and fasting blood glucose in pregnant women with insufficient or deficient vitamin D: a randomized, placebo-controlled trial.BMC endocrine disorders · 2022Trial
- Uncovering Modifiable Contributors to Depressive Symptoms During Antidepressant Prescription Renewal: A Primary Care Case Report.Clinical case reports · 2026Article
- Clinical Benefits and Safety of Multiple Micronutrient Supplementation During Preconception, Pregnancy, and Lactation: A Review.Nutrition reviews · 2025Review
- Article
- A network analysis of nutritional markers and maternal perinatal mental health in the French EDEN cohort.BMC pregnancy and childbirth · 2023Article
- Postpartum depression: aetiology, pathogenesis and the role of nutrients and dietary supplements in prevention and management.Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023Review
- Sex differences in depression: An immunological perspective.Brain research bulletin · 2023Review
- Review
- The syndemic effects of food insecurity, water insecurity, and HIV on depressive symptomatology among Kenyan women.Social science & medicine (1982) · 2022Observational
- The synergistic effects of short inter-pregnancy interval and micronutrients deficiency on third-trimester depression.Frontiers in nutrition · 2022Article
- Postpartum Diet and the Lifestyle of Korean and Chinese Women: A Comparative Study.Frontiers in public health · 2022Article
- Healthy eating and physical activity among breastfeeding women: the role of misinformation.BMC pregnancy and childbirth · 2020Article
- PPAR and functional foods: Rationale for natural neurosteroid-based interventions for postpartum depression.Neurobiology of stress · 2020Article
- Association of antepartum vitamin D deficiency with postpartum depression: a clinical perspective.Public health nutrition · 2020Review
- Is Vitamin D Status Associated with Depression, Anxiety and Sleep Quality in Pregnancy: A Systematic Review.Advanced biomedical research · 2020Article
- Association between Postpartum Nutritional Status and Postpartum Depression Symptoms.Nutrients · 2019Article
- Ω-3 fatty acids-supplementary in gestation alleviates neuroinflammation and modulates neurochemistry in rats.Lipids in health and disease · 2018Article
- The Prevalence of Postpartum Depression and Its Association with Food Insecurity among Mothers Referring to Community Health Centers.Iranian journal of psychiatry · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Postpartum depression (PPD) is a relatively common and often severe mood disorder that develops in women after childbirth. The aetiology of PPD is unclear, although there is emerging evidence to suggest a psychoneuroimmune connection. Additionally, deficiencies in n-3 PUFA, B vitamins, vitamin D and trace minerals have been implicated. This paper reviews evidence for a link between micronutrient status and PPD, analysing the potential contribution of each micronutrient to psychoneuroimmunological mechanisms of PPD. Articles related to PPD and women's levels of n-3 PUFA, B vitamins, vitamin D and the trace minerals Zn and Se were reviewed. Findings suggest that while n-3 PUFA levels have been shown to vary inversely with PPD and link with psychoneuroimmunology, there is mixed evidence regarding the ability of n-3 PUFA to prevent or treat PPD. B vitamin status is not clearly linked to PPD, even though it seems to vary inversely with depression in non-perinatal populations and may have an impact on immunity. Vitamin D and the trace minerals Zn and Se are linked to PPD and psychoneuroimmunology by intriguing, but small, studies. Overall, evidence suggests that certain micronutrient deficiencies contribute to the development of PPD, possibly through psychoneuroimmunological mechanisms. Developing a better understanding of these mechanisms is important for guiding future research, clinical practice and health education regarding PPD.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.