ArticleRadiation oncology (London, England)2012
Organizing pneumonia after stereotactic ablative radiotherapy of the lung.
Article in Radiation oncology (London, England), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 35 citations in OpenAlex.
- Article
- Radiation-induced organizing pneumonia caused by carbon-ion radiotherapy for lung cancer.Radiology case reports · 2024Article
- A pictorial essay on radiological changes after stereotactic body radiation therapy for lung tumors.Japanese journal of radiology · 2022Review
- Demystifying idiopathic interstitial pneumonia: time for more etiology-focused nomenclature in interstitial lung disease.Expert review of respiratory medicine · 2022Review
- Treatment and outcome of a patient with radiation-induced organizing pneumonia in the context of coronavirus disease 2019 (COVID-19).Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology · 2021Article
- Computerized tomography-Guided Microwave Ablation of Patients with Stage I Non-small Cell Lung Cancers: A Single-Institution Retrospective Study.Journal of clinical imaging science · 2021Article
- Organizing pneumonia after thoracic radiotherapy followed by anti-PD-1 antibody treatment for patients with lung cancer: Three case reports.Thoracic cancer · 2019Article
- Spontaneous resolution of thoracic radiation therapy-induced organizing pneumonia: A case series.Respiratory medicine case reports · 2019Article
- Irradiation enhanced risks of hospitalised pneumonopathy in lung cancer patients: a population-based surgical cohort study.BMJ open · 2017Article
- Radiation-Induced Organizing Pneumonia: A Characteristic Disease that Requires Symptom-Oriented Management.International journal of molecular sciences · 2017Review
- Radiation-induced organizing pneumonia after stereotactic body radiotherapy for lung tumor.Journal of radiation research · 2015Article
- Stereotactic body radiotherapy with helical TomoTherapy for medically inoperable early stage primary and second-primary non-small-cell lung neoplasm: 1-year outcome and toxicity analysis.The British journal of radiology · 2015Article
- Feasibility study of stereotactic body radiotherapy for peripheral lung tumors with a maximum dose of 100 Gy in five fractions and a heterogeneous dose distribution in the planning target volume.Journal of radiation research · 2014Article
- Cryptogenic organizing pneumonia associated with radiation: A report of two cases.Oncology letters · 2014Article
- Relationship between radiation pneumonitis and organizing pneumonia after radiotherapy for breast cancer.Radiation oncology (London, England) · 2013Article
- Radiation-triggered acute exacerbation of progressive fibrotic interstitial lung diseases: 'Are we advancing the frontier or crossing a dangerous line?'Therapeutic advances in respiratory diseaseReview
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9 authors at 3 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundOrganizing pneumonia (OP), so called bronchiolitis obliterans organizing pneumonia after postoperative irradiation for breast cancer has been often reported. There is little information about OP after other radiation modalities. This cohort study investigated the clinical features and risk factors of OP after stereotactic ablative radiotherapy of the lung (SABR).
methodsPatients undergoing SABR between 2004 and 2010 in two institutions were investigated. Blood test and chest computed tomography were performed at intervals of 1 to 3 months after SABR. The criteria for diagnosing OP were: 1) mixture of patchy and ground-glass opacity, 2) general and/or respiratory symptoms lasting for at least 2 weeks, 3) radiographic lesion in the lung volume receiving < 0.5 Gy, and 4) no evidence of a specific cause.
resultsAmong 189 patients (164 with stage I lung cancer and 25 with single lung metastasis) analyzed, nine developed OP. The incidence at 2 years was 5.2% (95% confidence interval; 2.6-9.3%). Dyspnea were observed in all patients. Four had fever. These symptoms and pulmonary infiltration rapidly improved after corticosteroid therapy. Eight patients had presented with symptomatic radiation pneumonitis (RP) around the tumor 2 to 7 months before OP. The prior RP history was strongly associated with OP (hazard ratio 61.7; p = 0.0028) in multivariate analysis.
conclusionsThis is the first report on OP after SABR. The incidence appeared to be relatively high. The symptoms were sometimes severe, but corticosteroid therapy was effective. When patients after SABR present with unusual pneumonia, OP should be considered as a differential diagnosis, especially in patients with prior symptomatic RP.
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