ArticleSubstance abuse treatment, prevention, and policy2012
Improvement of quality of life following 6 months of methadone maintenance therapy in Malaysia.
Article in Substance abuse treatment, prevention, and policy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- The effectiveness of compulsory drug treatment: A systematic review.The International journal on drug policy · 2016Pooled it
- Changes in quality of life (WHOQOL-BREF) and addiction severity index (ASI) among participants in opioid substitution treatment (OST) in low and middle income countries: an international systematic review.Drug and alcohol dependence · 2014Pooled it
- Changes in Quality of Life following Buprenorphine Treatment: Relationship with Treatment Retention and Illicit Opioid Use.Journal of psychoactive drugsTrial
- Improved Quality of Life Following Addiction Treatment Is Associated with Reductions in Substance Use.Journal of clinical medicine · 2019Article
- HIV knowledge and risk behaviors among drug users in three Vietnamese mountainous provinces.Substance abuse treatment, prevention, and policy · 2019Article
- Association between severity of illicit drug dependence and quality of life in a psychosocial care center in BRAZIL: cross-sectional study.Health and quality of life outcomes · 2017Article
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- Article
- Comparison and concordance of health-related quality of life tests among substance users.Health and quality of life outcomes · 2015Article
- Improvement of quality of life in methadone treatment patients in northern Taiwan: a follow-up study.BMC psychiatry · 2013Article
- Take home maintenance medication in opiate dependence.Deutsches Arzteblatt international · 2013Article
- Article
- Profile of clients attending a methadone clinic.The Malaysian journal of medical sciences : MJMSArticle
- Quality of life in methadone maintenance treated patients in Long An, a southern province of Vietnam.Health psychology openArticle
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMethadone Maintenance Therapy (MMT) is one of the popular choices for drug substitution therapy and is fairly new in Malaysia. Aside from its role in harm reduction against HIV infection, MMT programme may potentially enhances clients' quality of life. This study aims to identify the impact of MMT programme on clients' quality of life after 6 months in treatment and to explore factors that may be associated with changes in their quality of life.
methodsIn this retrospective report review, 122 subjects from 2 government MMT clinics were selected from the district of Tampin, Negeri Sembilan, Malaysia. The raw score from the WHO Quality of Life questionnaire (WHOQOL-BREF), at baseline and 6 months after therapy were collected and converted to 0-100 scale form to give quality of life scores for four domains; physical, psychological, social relationships and environment. Other variables of interest were socio-demography, age when joining MMT programme, age and duration of illicit drug use, HIV and Hepatitis C status, and the Opiate Treatment Index (OTI) score on drug use, sexual and social aspect at the baseline. Statistical analysis used the SPSS version 16.
resultsThere was significant improvement in all four domains of quality of life, after 6 months of MMT. The largest improvement was for psychological domain (mean score difference 15.54 ± 20.81). Multivariable linear regression analysis showed that, for the physical domain, there was no significant predictor. For both the psychological and social domains, having tertiary education is a significant predictor for improvement in both aspects of quality of life. Negative HIV status is associated with improvement for the environment domain.
conclusionsThere was a significant short term improvement in the quality of life of MMT clients who stayed in the programme for at least 6 months in the district of Tampin, Negeri Sembilan, Malaysia.
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