Evidence map›Paper›PMID 22852560›Full record

Trial reportTrials2012

Examining the impact of genetic testing for type 2 diabetes on health behaviors: study protocol for a randomized controlled trial.

Corrine I Voils, Cynthia J Coffman, David Edelman, Matthew L Maciejewski, Janet M Grubber, Azita Sadeghpour, Alex Cho, Jamiyla McKenzie, Francoise Blanpain, Maren Scheuner and 4 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Trials, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01060540 (The Impact of Genetic Testing for Type 2 Diabetes on Health Behaviors), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01060540 nacompletednot on this map

The Impact of Genetic Testing for Type 2 Diabetes on Health Behaviors

TypeinterventionalSponsorUS Department of Veterans AffairsRan2010 to 2013Enrolled601ConditionsDiabetes MellitusArmsgenetic testing for type 2 diabetes, Conventional risk counseling, eye disease counseling
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

Corrine I VoilsCenter for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, Durham, NC, USA. corrine.voils@dm.duke.edu
Cynthia J Coffman
David Edelman
Matthew L Maciejewski
Janet M Grubber
Azita Sadeghpour
Alex Cho
Jamiyla McKenzie
Francoise Blanpain
Maren Scheuner
Margarete Sandelowski
M Patrick Gallagher
Geoffrey S Ginsburg
William S Yancy
Durham VA Medical Center · USDuke Medical Center · USDuke University Hospital · USDuke University · USUniversity of North Carolina at Chapel Hill · USVA Greater Los Angeles Healthcare System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe describe the study design, procedures, and development of the risk counseling protocol used in a randomized controlled trial to evaluate the impact of genetic testing for diabetes mellitus (DM) on psychological, health behavior, and clinical outcomes. METHODS/

designEligible patients are aged 21 to 65 years with body mass index (BMI) ≥27 kg/m(2) and no prior diagnosis of DM. At baseline, conventional DM risk factors are assessed, and blood is drawn for possible genetic testing. Participants are randomized to receive conventional risk counseling for DM with eye disease counseling or with genetic test results. The counseling protocol was pilot tested to identify an acceptable graphical format for conveying risk estimates and match the length of the eye disease to genetic counseling. Risk estimates are presented with a vertical bar graph denoting risk level with colors and descriptors. After receiving either genetic counseling regarding risk for DM or control counseling on eye disease, brief lifestyle counseling for prevention of DM is provided to all participants. DISCUSSION: A standardized risk counseling protocol is being used in a randomized trial of 600 participants. Results of this trial will inform policy about whether risk counseling should include genetic counseling.

trial registrationClinicalTrials.gov Identifier NCT01060540.

Indexed as

Genetic CounselingGenetic TestingHealth BehaviorHealth Knowledge, Attitudes, PracticeResearch DesignAdultAgedDiabetes Mellitus, Type 2FemaleGenetic Predisposition to DiseaseHumansMaleMiddle AgedNorth CarolinaPatient SelectionPredictive Value of Tests

Identifiers

PMID22852560
PMCPMC3464684
OpenAlexW2110204385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.