ReviewNutrients2012
Wine, beer, alcohol and polyphenols on cardiovascular disease and cancer.
Review in Nutrients, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02869763 (Dose-response Effect of Alcohol Ingestion on Steroid Profile), which is not on this map. Cited by 206 papers, 12 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dose-response Effect of Alcohol Ingestion on Steroid Profile: Gender and Ethnic Aspects
Who cites it
206 citing papers in PubMed, 12 syntheses or guidelines pooled it, 524 citations in OpenAlex.
- Pooled it
- Maternal smoking, consumption of alcohol, and caffeinated beverages during pregnancy and the risk of childhood brain tumors: a meta-analysis of observational studies.BMC public health · 2024Pooled it
- Potential neuroprotective effects of fermented foods and beverages in old age: a systematic review.Frontiers in nutrition · 2023Pooled it
- Alcohol Consumption and Cardiovascular Health.The American journal of medicine · 2022Pooled it
- Alcohol and Health Outcomes: An Umbrella Review of Meta-Analyses Base on Prospective Cohort Studies.Frontiers in public health · 2022Pooled it
- Cardiovascular Effects of Chocolate and Wine-Narrative Review.Nutrients · 2021Pooled it
- The Effect of Green Coffee Bean Extract on Cardiovascular Risk Factors: A Systematic Review and Meta-analysis.Advances in experimental medicine and biology · 2021Pooled it
- [Differential health effects of alcoholic beverages: an umbrella review of observational studies.]Revista espanola de salud publica · 2020Pooled it
- Diet and risk of diabetic retinopathy: a systematic review.European journal of epidemiology · 2018Pooled it
- Moderate alcohol consumption and atherosclerosis : Meta-analysis of effects on lipids and inflammation.Wiener klinische Wochenschrift · 2017Pooled it
- Alcoholic beverage preference and diabetes incidence across Europe: the Consortium on Health and Ageing Network of Cohorts in Europe and the United States (CHANCES) project.European journal of clinical nutrition · 2017Pooled it
- The relationship between mild alcohol consumption and mortality in Koreans: a systematic review and meta-analysis.BMC public health · 2015Pooled it
- Trial
- Influence of daily beer or ethanol consumption on physical fitness in response to a high-intensity interval training program. The BEER-HIIT study.Journal of the International Society of Sports Nutrition · 2020Trial
- Trial
- Phytochemical uptake following human consumption of Montmorency tart cherry (L. Prunus cerasus) and influence of phenolic acids on vascular smooth muscle cells in vitro.European journal of nutrition · 2016Trial
- Polyphenol intake and mortality risk: a re-analysis of the PREDIMED trial.BMC medicine · 2014Trial
- A Comprehensive Study of Hops (Plants (Basel, Switzerland) · 2026Review
- Interpreting the Evidence on Wine Consumption and Health: A Narrative Review of the J-Shaped Association and Contemporary Alcohol Guidelines.Nutrients · 2026Review
- Beer Consumption and Health: A Bibliometric Analysis of Five Decades of Scientific Literature.Foods (Basel, Switzerland) · 2026Review
146 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since ancient times, people have attributed a variety of health benefits to moderate consumption of fermented beverages such as wine and beer, often without any scientific basis. There is evidence that excessive or binge alcohol consumption is associated with increased morbidity and mortality, as well as with work related and traffic accidents. On the contrary, at the moment, several epidemiological studies have suggested that moderate consumption of alcohol reduces overall mortality, mainly from coronary diseases. However, there are discrepancies regarding the specific effects of different types of beverages (wine, beer and spirits) on the cardiovascular system and cancer, and also whether the possible protective effects of alcoholic beverages are due to their alcoholic content (ethanol) or to their non-alcoholic components (mainly polyphenols). Epidemiological and clinical studies have pointed out that regular and moderate wine consumption (one to two glasses a day) is associated with decreased incidence of cardiovascular disease (CVD), hypertension, diabetes, and certain types of cancer, including colon, basal cell, ovarian, and prostate carcinoma. Moderate beer consumption has also been associated with these effects, but to a lesser degree, probably because of beer's lower phenolic content. These health benefits have mainly been attributed to an increase in antioxidant capacity, changes in lipid profiles, and the anti-inflammatory effects produced by these alcoholic beverages. This review summarizes the main protective effects on the cardiovascular system and cancer resulting from moderate wine and beer intake due mainly to their common components, alcohol and polyphenols.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.