ArticleArchives of medical science : AMS2012
Carotid intima-media thickness and arterial stiffness in type 1 diabetic patients with and without microangiopathy.
Article in Archives of medical science : AMS, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 18 citations in OpenAlex.
- Association Between Morning Blood Pressure Surge and Tinnitus in Hypertensive Patients: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2026Article
- Sudomotor dysfunction reflects early atherosclerosis risk in adults with type 1 diabetes.Scientific reports · 2026Article
- Relationship between bleeding risk and arterial stiffness in patients with cerebral aneurysms.Turkish journal of medical sciences · 2025Article
- Emerging roles of i-motif in gene expression and disease treatment.Frontiers in pharmacology · 2023Review
- Impaired flow-mediated dilation response and carotid intima-media thickness in patients with type 1 diabetes mellitus with a mean disease duration of 4.1 years.Archives of endocrinology and metabolism · 2017Article
- Plasma soluble CD36, carotid intima-media thickness and cognitive function in patients with type 2 diabetes.Archives of medical science : AMS · 2017Article
- Central wave reflection is associated with peripheral arterial resistance in addition to arterial stiffness in subjects without antihypertensive medication.BMC cardiovascular disorders · 2016Article
- Adding carotid total plaque area to the Framingham risk score improves cardiovascular risk classification.Archives of medical science : AMS · 2016Article
- Patients with diabetes type 1 and thyroid autoimmunity have low prevalence of microangiopathic complications.Endocrine · 2016Article
- Peripheral vascular stiffness, assessed with two-dimensional speckle tracking versus the degree of coronary artery calcification, evaluated by tomographic coronary artery calcification index.Archives of medical science : AMS · 2015Article
- Application of multiscale entropy in arterial waveform contour analysis in healthy and diabetic subjects.Medical & biological engineering & computing · 2015Article
- Role of ultrasonography in the evaluation of correlation between strain and elasticity of common carotid artery in patients with diabetic nephropathy.International journal of clinical and experimental medicine · 2015Article
- Lipid, blood pressure and kidney update 2013.International urology and nephrology · 2014Review
- Influence of lifestyle on the course of type 1 diabetes mellitus.Archives of medical science : AMS · 2014Article
- Arterial distensibility in patients with ruptured and unruptured intracranial aneurysms: is it a predisposing factor for rupture risk?Medical science monitor : international medical journal of experimental and clinical research · 2013Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of the study was to assess carotid intima-media thickness (CIMT) as a subclinical marker of atherosclerosis and arterial stiffness in type 1 diabetic patients in relation to microangiopathy. MATERIAL AND
methodsWe included 87 type 1 diabetic patients (44 women, 43 men), median age 34 years (interquartile range [IQR] 29-43), median disease duration 10 years (IQR: 9-14), mean ± standard deviation (SD) glycated haemoglobin (HbA(1c)) 8.4 ±1.4%. Fifty patients had at least one microangiopathic complication. Intima-media thickness (IMT) of the common carotid artery was measured using high resolution ultrasonography. Arterial stiffness was assessed using digital volume pulse analysis and tonometric measurement of wave reflection and central haemodynamics.
resultsSUBJECTS WITH MICROANGIOPATHY COMPARED WITH THOSE WITHOUT HAD HIGHER VALUES OF CIMT (MEDIAN [IQR]: 0.53 mm [0.45-0.60 mm] vs 0.47 mm [0.34-0.52 mm], p = 0.002), higher central augmentation index (CAI(x)) (mean ± SD: 120.2 ±19.4% vs. 110.5 ±17.1%, p = 0.016) and higher peripheral augmentation index (PAI(x)) (65.7 ±18.1% vs. 57.2 ±14.9%, p = 0.023). In the logistic regression analysis, the duration of diabetes, systolic and diastolic blood pressure, postprandial glycaemia, HbA(1c) and triglycerides predicted the presence of diabetic microangiopathy independently of age and sex. The CIMT, CAI(x) and PAI(x) were associated with the presence of diabetic microangiopathy only in the univariate model.
conclusionsIn type 1 diabetic patients with microangiopathic complications, increased carotid IMT and arterial stiffness were observed. The study confirms the role of traditional risk factors for late diabetic complications, such as the duration of the disease and metabolic control in the development of microangiopathy.
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