Evidence map›Paper›PMID 22851961›Full record

ArticleCardiorenal medicine2012

Myocardial Stunning with Hemodialysis: Clinical Challenges of the Cardiorenal Patient.

Mozow Y Zuidema, Kevin C Dellsperger

Open access · bronzeAbstract read
In one paragraph

Article in Cardiorenal medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 46 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mozow Y ZuidemaDivision of Cardiovascular Medicine, Department of Internal Medicine, Columbia, Mo., USA.
Kevin C Dellsperger
University of Missouri · US

Funding

Role of Cytokine-Induced Inflammation in Endothelial Dysfunction in DiabetesR01HL085119 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI HILL, MICHAEL A · 2007 to 2015
$3.1M
Mechanisms of Reperfusion-induced Endothelial InjuryR01HL077566 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI HILL, MICHAEL A · 2006 to 2010
$1.8M
American Heart Association-American Stroke Association 10POST3870022NHLBI NIH HHS R01 HL077566NHLBI NIH HHS R01 HL085119
6 · The paper itself

Abstract

We discuss the current state of knowledge related to the pathogenesis of myocardial stunning as well as the potential mechanisms responsible for the clinical presentation of myocardial stunning in hemodialysis patients. We suggest future research areas for this critical and clinically important condition in this high-risk patient population. In consideration of acute and chronic changes secondary to dialysis, especially in patients with risk for coronary artery disease, the prevalence of myocardial stunning and its role in the natural history of these patients' disease progression is considered. We propose a paradigm: that the majority of the pathophysiologic mechanisms by which hemodialysis may induce myocardial stunning falls into two categories with (1) vascular and/or (2) metabolic contributions. In order to prevent eventual myocardial hibernation, myocardial remodeling, scarring, and loss of contractile function with aberrant electrical conductivity that could lead to sudden death, it is imperative to identify the risk factors associated with myocardial stunning during hemodialysis. Further understanding of these mechanisms may lead to novel clinical interventions and pharmacologic therapeutic agents.

Identifiers

PMID22851961
PMCPMC3376339
OpenAlexW2037878176

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.