Evidence map›Paper›PMID 22851927›Full record

ArticleMarine drugs2012

Lochmolins A-G, new sesquiterpenoids from the soft coral Sinularia lochmodes.

Yen-Ju Tseng, Kuo-Ping Shen, Hui-Li Lin, Chiung-Yao Huang, Chang-Feng Dai, Jyh-Horng Sheu

Abstract read
In one paragraph

Article in Marine drugs, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yen-Ju TsengDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Kuo-Ping ShenDepartment of Nursing, Meiho University, Pingtung 912, Taiwan.
Hui-Li LinDepartment of Food and Nutrition, Meiho University, Pingtung 912, Taiwan.
Chiung-Yao HuangDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.
Chang-Feng DaiInstitute of Oceanography, National Taiwan University, Taipei 112, Taiwan.
Jyh-Horng SheuDepartment of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seven new sesquiterpenoids, lochmolins A-G (1-7), were isolated from a Taiwanese soft coral Sinularia lochmodes. The structures of these metabolites were elucidated by extensive spectroscopic study. Compounds 1-4 were found to inhibit the accumulation of the LPS-induced pro-inflammatory COX-2 protein in RAW264.7 macrophage cells.

Indexed as

AnimalsAnthozoaCell LineCyclooxygenase 2 InhibitorsMagnetic Resonance SpectroscopySesquiterpenesCyclooxygenase 2 InhibitorsSesquiterpenesaromadendranegermacranesesquiterpenesSinularia lochmodessoft coral

Identifiers

PMID22851927
PMCPMC3407932

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.