Evidence map›Paper›PMID 22851924›Full record

ArticleMarine drugs2012

4-Methylenesterols from a sponge Theonella swinhoei.

Jheng-Kun Guo, Ching-Ying Chiang, Mei-Chin Lu, Wen-Been Chang, Jui-Hsin Su

Abstract read
In one paragraph

Article in Marine drugs, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Marine drugs · 2023
    Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jheng-Kun GuoNational Museum of Marine Biology & Aquarium, Pingtung 944, Taiwan.
Ching-Ying ChiangCenter of General Studies, National Kaohsiung Marine University, Kaohsiung 811, Taiwan.
Mei-Chin LuNational Museum of Marine Biology & Aquarium, Pingtung 944, Taiwan.
Wen-Been ChangNational Museum of Marine Biology & Aquarium, Pingtung 944, Taiwan.
Jui-Hsin SuNational Museum of Marine Biology & Aquarium, Pingtung 944, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three new 4-methylenesterols, theonellasterol K (1), acetyltheonellasterol (2) and acetyldehydroconicasterol (3), along with two known sterols, theonellasterol (4) and theonellasterone (5), were isolated from the sponge Theonella swinhoei. The structures of these compounds were elucidated on the basis of their spectroscopic data and comparison of the NMR data with those of known analogues. Compound 1 exhibited significant cytotoxic activity against HCT-116, K562 and Molt 4 cancer cell lines.

Indexed as

AnimalsAntineoplastic AgentsHCT116 CellsHumansK562 CellsMagnetic Resonance SpectroscopySterolsTheonellaAntineoplastic AgentsSterols4-methylenesterolsspongeTheonella

Identifiers

PMID22851924
PMCPMC3407929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.