ArticleDevelopmental psychobiology2013
Social context induces two unique patterns of c-Fos expression in adolescent and adult rats.
Article in Developmental psychobiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Isolation driven changes in Iba1-positive microglial morphology are associated with social recognition memory in adults and adolescents.Neurobiology of learning and memory · 2022Article
- Mu opioid receptors in the medial preoptic area govern social play behavior in adolescent male rats.Genes, brain, and behavior · 2020Article
- Anxious to see you: Neuroendocrine mechanisms of social vigilance and anxiety during adolescence.The European journal of neuroscience · 2020Article
- Social Interaction With an Alcohol-Intoxicated or Cocaine-Injected Peer Selectively Alters Social Behaviors and Drinking in Adolescent Male and Female Rats.Alcoholism, clinical and experimental research · 2019Article
- Fos activation patterns related to acute ethanol and conditioned taste aversion in adolescent and adult rats.Alcohol (Fayetteville, N.Y.) · 2019Article
- From adolescence to late aging: A comprehensive review of social behavior, alcohol, and neuroinflammation across the lifespan.International review of neurobiology · 2019Review
- Late aging alters behavioral sensitivity to ethanol in a sex-specific manner in Fischer 344 rats.Pharmacology, biochemistry, and behavior · 2018Article
- Analysis of c-Fos induction in response to social interaction in male and female Fisher 344 rats.Brain research · 2017Article
- Immediate early gene expression reveals interactions between social and nicotine rewards on brain activity in adolescent male rats.Behavioural brain research · 2016Article
- Distinct neuronal activation patterns are associated with PCP-induced social withdrawal and its reversal by the endocannabinoid-enhancing drug URB597.Neuroscience research · 2016Article
- Role of the oxytocin system in amygdala subregions in the regulation of social interest in male and female rats.Neuroscience · 2016Article
- Prior extended daily access to cocaine elevates the reward threshold in a conditioned place preference test.Addiction biology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The study assessed possible age differences in brain activation patterns to low dose ethanol (.5 g/kg intraperitoneally) and the influence of social context on this activation. Early adolescent or young adult male Sprague-Dawley rats were placed either alone or with an unfamiliar partner of the same age and sex following saline or ethanol administration. c-Fos protein immunoreactivity was used to index neuronal activation in 15 regions of interest. Ethanol had little effect on c-Fos activation. In adolescents, social context activated an "autonomic" network including the basolateral and central amygdala, bed nucleus of the stria terminalis, lateral hypothalamus, and lateral septum. In contrast, when adult rats were alone, activation was evident in a "reward" network that included the substantia nigra, nucleus accumbens, anterior cingulate and orbitofrontal cortices, lateral parabrachial nucleus, and locus coeruleus.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.