Evidence map›Paper›PMID 22850230›Full record

ArticleHealth physics2012

Electron paramagnetic resonance dosimetry for a large-scale radiation incident.

Harold M Swartz, Ann Barry Flood, Benjamin B Williams, Ruhong Dong, Steven G Swarts, Xiaoming He, Oleg Grinberg, Jason Sidabras, Eugene Demidenko, Jiang Gui and 13 more

Abstract read
In one paragraph

Article in Health physics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Celebration of 80 years of EPR.Applied magnetic resonance · 2024
    Article
  2. Article
  3. Review
  4. Article
  5. EPR Everywhere.Applied magnetic resonance · 2021
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Imaging tooth enamel using zero echo time (ZTE) magnetic resonance imaging.Proceedings of SPIE--the International Society for Optical Engineering · 2015
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Harold M SwartzDartmouth Medical School, Hanover, NH 03755, USA. harold.m.swartz@dartmouth.edu
Ann Barry Flood
Benjamin B Williams
Ruhong Dong
Steven G Swarts
Xiaoming He
Oleg Grinberg
Jason Sidabras
Eugene Demidenko
Jiang Gui
David J Gladstone
Lesley A Jarvis
Maciej M Kmiec
Kyo Kobayashi
Piotr N Lesniewski
Stephen D P Marsh
Thomas P Matthews
Roberto J Nicolalde
Patrick M Pennington
Timothy Raynolds
Ildar Salikhov
Dean E Wilcox
Bassem I Zaki

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Scientific and Administrative Core: Dartmouth Medical SchoolU19AI091173 · NIAID · DARTMOUTH COLLEGE · PI SWARTS, STEVEN GREGORY · 2010 to 2014
$16.3M
NCI NIH HHS P30 CA023108NIAID NIH HHS U19 AI091173NIAID NIH HHS U19AI091173
6 · The paper itself

Abstract

With possibilities for radiation terrorism and intensified concerns about nuclear accidents since the recent Fukushima Daiichi event, the potential exposure of large numbers of individuals to radiation that could lead to acute clinical effects has become a major concern. For the medical community to cope with such an event and avoid overwhelming the medical care system, it is essential to identify not only individuals who have received clinically significant exposures and need medical intervention but also those who do not need treatment. The ability of electron paramagnetic resonance to measure radiation-induced paramagnetic species, which persist in certain tissues (e.g., teeth, fingernails, toenails, bone, and hair), has led to this technique becoming a prominent method for screening significantly exposed individuals. Although the technical requirements needed to develop this method for effective application in a radiation event are daunting, remarkable progress has been made. In collaboration with General Electric and through funding committed by the Biomedical Advanced Research and Development Authority, electron paramagnetic resonance tooth dosimetry of the upper incisors is being developed to become a Food and Drug Administration-approved and manufacturable device designed to carry out triage for a threshold dose of 2 Gy. Significant progress has also been made in the development of electron paramagnetic resonance nail dosimetry based on measurements of nails in situ under point-of-care conditions, and in the near future this may become a second field-ready technique. Based on recent progress in measurements of nail clippings, it is anticipated that this technique may be implementable at remotely located laboratories to provide additional information when the measurements of dose on-site need to be supplemented. The authors conclude that electron paramagnetic resonance dosimetry is likely to be a useful part of triage for a large-scale radiation incident.

Indexed as

Radioactive Hazard ReleaseArtifactsElectron Spin Resonance SpectroscopyEnvironmental ExposureHumansMechanical PhenomenaNailsRadiometryToothTriage

Identifiers

PMID22850230
PMCPMC3649772

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.