Evidence map›Paper›PMID 22850124›Full record

ArticlePhysics in medicine and biology2012

Quantitative analysis of rectal cancer by spectral domain optical coherence tomography.

Q Q Zhang, X J Wu, T Tang, S W Zhu, Q Yao, Bruce Z Gao, X C Yuan

Abstract read
In one paragraph

Article in Physics in medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The clinical usefulness of optical coherence tomography during cancer interventions.Journal of cancer research and clinical oncology · 2018
    Pooled it
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  9. Advances in endoscopy for colorectal polyp detection and classification.Proceedings (Baylor University. Medical Center) · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Q Q ZhangKey Laboratory of Optical Information Science and Technology, Institute of Modern Optics, Ministry of Education of China, Nankai University, Tianjin 300071, People's Republic of China.
X J Wu
T Tang
S W Zhu
Q Yao
Bruce Z Gao
X C Yuan

Funding

UNDERSTANDING AND CONTROLLING TISSUE-SPECIFIC VASCULAR PATTERNINGP20RR021949 · NCRR · CLEMSON UNIVERSITY · PI MARKWALD, ROGER R · 2009 to 2011
$5.2M
Differentiation of Bone-Marrow Stem Cells in a Laser Patterned Myocyte CocultureK25HL088262 · NHLBI · CLEMSON UNIVERSITY · PI GAO, BRUCE Z · 2007 to 2011
$715k
NCRR NIH HHS P20 RR021949NHLBI NIH HHS K25 HL088262
6 · The paper itself

Abstract

To quantify OCT images of rectal tissue for clinic diagnosis, the scattering coefficient of the tissue is extracted by curve fitting the OCT signals to a confocal single model. A total of 1000 measurements (half and half of normal and malignant tissues) were obtained from 16 recta. The normal rectal tissue has a larger scattering coefficient ranging from 1.09 to 5.41 mm⁻¹ with a mean value of 2.29 mm⁻¹ (std:±0.32), while the malignant group shows lower scattering property and the values ranging from 0.25 to 2.69 mm⁻¹ with a mean value of 1.41 mm⁻¹ (std:±0.18). The peri-cancer of recta has also been investigated to distinguish the difference between normal and malignant rectal tissue. The results demonstrate that the quantitative analysis of the rectal tissue can be used as a promising diagnostic criterion of early rectal cancer, which has great value for clinical medical applications.

Indexed as

AgedAged, 80 and overFemaleHumansMaleMiddle AgedRectal NeoplasmsRectumTomography, Optical Coherence

Identifiers

PMID22850124
PMCPMC3691818

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.