ReviewNeural plasticity2012
Enriched and deprived sensory experience induces structural changes and rewires connectivity during the postnatal development of the brain.
Review in Neural plasticity, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 54 citations in OpenAlex.
- Complex Three-Dimensional Rearing Environments Amplify Compensatory Plasticity Following Early Blindness.eNeuro · 2026Article
- Sensory Deprivation and the Brain: Neurobiological Mechanisms, Psychological Effects, and Clinical Implications.Brain sciences · 2026Review
- The role of sensory experience in the maturation of prefrontal cortical circuits.Frontiers in neuroscience · 2026Review
- Differential impacts of social isolation and enriched environment on multi-sensory brain-wide functionality and network segregation.Nature communications · 2025Article
- Cross brain reshaping in congenital visual or hearing impairment: triple-network dysfunction.Brain communications · 2025Article
- Article
- The Newborn's Reaction to Light as the Determinant of the Brain's Activation at Human Birth.Frontiers in integrative neuroscience · 2022Article
- Cognitive decline in acoustic neuroma patients: An investigation based on resting-state functional magnetic resonance imaging and voxel-based morphometry.Frontiers in psychiatry · 2022Article
- Article
- Early impoverished environment delays the maturation of cerebral cortex.Scientific reports · 2018Article
- Exposure to complex environments results in more sparse representations of space in the hippocampus.Hippocampus · 2017Article
- The normal environment delays the development of multisensory integration.Scientific reports · 2017Article
- Blindfolding during wakefulness causes decrease in sleep slow wave activity.Physiological reports · 2017Article
- Alterations in gray matter volume due to unilateral hearing loss.Scientific reports · 2016Article
- Strategies for tonal and atonal musical interpretation in blind and normally sighted children: an fMRI study.Brain and behavior · 2016Article
- PPREMO: a prospective cohort study of preterm infant brain structure and function to predict neurodevelopmental outcome.BMC pediatrics · 2015Observational
- Functional connectivity of visual cortex in the blind follows retinotopic organization principles.Brain : a journal of neurology · 2015Article
- Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice.Nature communications · 2015Article
- Fractality of sensations and the brain health: the theory linking neurodegenerative disorder with distortion of spatial and temporal scale-invariance and fractal complexity of the visible world.Frontiers in aging neuroscience · 2015Article
- A critical period for postnatal adaptive plasticity in a model of motor axon miswiring.PloS one · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
During postnatal development, sensory experience modulates cortical development, inducing numerous changes in all of the components of the cortex. Most of the cortical changes thus induced occur during the critical period, when the functional and structural properties of cortical neurons are particularly susceptible to alterations. Although the time course for experience-mediated sensory development is specific for each system, postnatal development acts as a whole, and if one cortical area is deprived of its normal sensory inputs during early stages, it will be reorganized by the nondeprived senses in a process of cross-modal plasticity that not only increases performance in the remaining senses when one is deprived, but also rewires the brain allowing the deprived cortex to process inputs from other senses and cortices, maintaining the modular configuration. This paper summarizes our current understanding of sensory systems development, focused specially in the visual system. It delineates sensory enhancement and sensory deprivation effects at both physiological and anatomical levels and describes the use of enriched environment as a tool to rewire loss of brain areas to enhance other active senses. Finally, strategies to apply restorative features in human-deprived senses are studied, discussing the beneficial and detrimental effects of cross-modal plasticity in prostheses and sensory substitution devices implantation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.