ArticlePloS one2012
ATP hydrolyzing salivary enzymes of caterpillars suppress plant defenses.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
33 citing papers in PubMed, 86 citations in OpenAlex.
- Novel effector HYPB1 of cotton bollworm (Helicoverpa armigera) inhibits biosynthesis of plant secondary metabolites and promotes feeding by targeting cotton dirigent protein GhDIR15.Journal of integrative plant biology · 2026Article
- Proteomic Variation in the Oral Secretion of Spodoptera exigua and Spodoptera littoralis Larvae in Response to Different food Sources.Journal of chemical ecology · 2025Article
- Characterization of the swede midge,Current research in insect science · 2023Article
- The dual function of elicitors and effectors from insects: reviewing the 'arms race' against plant defenses.Plant molecular biology · 2022Review
- Molecular and Biochemical Mechanisms of Elicitors in Pest Resistance.Life (Basel, Switzerland) · 2022Review
- Plant-phenotypic changes induced by parasitoid ichnoviruses enhance the performance of both unparasitized and parasitized caterpillars.Molecular ecology · 2021Article
- Article
- Damage Signaling by Extracellular Nucleotides: A Role for Cyclic Nucleotides in Elevating Cytosolic Free Calcium?Frontiers in plant science · 2021Article
- In silico identification of effector proteins from generalist herbivore Spodoptera litura.BMC genomics · 2020Article
- The Desaturase GeneInternational journal of molecular sciences · 2020Article
- Spodoptera frugiperda Caterpillars Suppress Herbivore-Induced Volatile Emissions in Maize.Journal of chemical ecology · 2020Article
- DORN1/P2K1 and purino-calcium signalling in plants: making waves with extracellular ATP.Annals of botany · 2020Article
- Breaking Bad News: Dynamic Molecular Mechanisms of Wound Response in Plants.Frontiers in plant science · 2020Review
- Expression Patterns, Molecular Characterization, and Response to Host Stress of CYP Genes fromInsects · 2019Article
- Phytohormones in Fall Armyworm Saliva Modulate Defense Responses in Plants.Journal of chemical ecology · 2019Article
- Role of CaInternational journal of molecular sciences · 2018Review
- Gut-Associated Bacteria of Helicoverpa zea Indirectly Trigger Plant Defenses in Maize.Journal of chemical ecology · 2018Article
- A crosstalk between extracellular ATP and jasmonate signaling pathways for plant defense.Plant signaling & behavior · 2018Article
- Extracellular ATP Acts on Jasmonate Signaling to Reinforce Plant Defense.Plant physiology · 2018Article
- Host plant driven transcriptome plasticity in the salivary glands of the cabbage looper (Trichoplusia ni).PloS one · 2017Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The oral secretions of herbivores are important recognition cues that can be used by plants to mediate induced defenses. In this study, a degradation of adenosine-5'-triphosphate (ATP) in tomato leaves was detected after treatment with Helicoverpa zea saliva. Correspondingly, a high level of ATPase activity in saliva was detected and three ATP hydrolyzing enzymes: apyrase, ATP synthase and ATPase 13A1 were identified in salivary glands. To determine the functions of these proteins in mediating defenses, they were cloned from H. zea and expressed in Escherichia coli. By applying the purified expressed apyrase, ATP synthase or ATPase 13A1 to wounded tomato leaves, it was determined that these ATP hydrolyzing enzymes suppressed the defensive genes regulated by the jasmonic acid and ethylene pathways in tomato plant. Suppression of glandular trichome production was also observed after treatment. Blood-feeding arthropods employ 5'-nucleotidase family of apyrases to circumvent host responses and the H. zea apyrase, is also a member of this family. The comparatively high degree of sequence similarity of the H. zea salivary apyrase with mosquito apyrases suggests a broader evolutionary role for salivary apyrases than previously envisioned.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.