ArticleFrontiers in microbiology2012
Metabolic Regulation of "Ca. Methylacidiphilum Fumariolicum" SolV Cells Grown Under Different Nitrogen and Oxygen Limitations.
Article in Frontiers in microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 35 citations in OpenAlex.
- C3 Compound Metabolism in the Thermoacidophilic Methanotroph Methylacidiphilum fumariolicum SolV.Environmental microbiology reports · 2025Article
- Identification and characterisation of a major outer membrane protein from Methylacidiphilum fumariolicum SolV.Antonie van Leeuwenhoek · 2023Article
- Verrucomicrobial methanotrophs grow on diverse C3 compounds and use a homolog of particulate methane monooxygenase to oxidize acetone.The ISME journal · 2021Article
- Article
- Verrucomicrobial methanotrophs: ecophysiology of metabolically versatile acidophiles.FEMS microbiology reviews · 2021Review
- Growth on Formic Acid Is Dependent on Intracellular pH Homeostasis for the Thermoacidophilic MethanotrophFrontiers in microbiology · 2021Article
- Article
- Geothermal Gases Shape the Microbial Community of the Volcanic Soil of Pantelleria, Italy.mSystems · 2020Article
- More Than a Methanotroph: A Broader Substrate Spectrum forFrontiers in microbiology · 2020Article
- Article
- The Acidophilic MethanotrophFrontiers in microbiology · 2019Article
- Highly Diverse Aquatic Microbial Communities Separated by Permafrost in Greenland Show Distinct Features According to Environmental Niches.Frontiers in microbiology · 2019Article
- Evolutionary History of Copper Membrane Monooxygenases.Frontiers in microbiology · 2018Article
- Methylacidiphilum fumariolicum SolV, a thermoacidophilic 'Knallgas' methanotroph with both an oxygen-sensitive and -insensitive hydrogenase.The ISME journal · 2017Article
- Distinct Network Interactions in Particle-Associated and Free-Living Bacterial Communities during aFrontiers in microbiology · 2017Article
- Ammonia Oxidation and Nitrite Reduction in the Verrucomicrobial MethanotrophFrontiers in microbiology · 2017Article
- Diverse electron sources support denitrification under hypoxia in the obligate methanotroph Methylomicrobium album strain BG8.Frontiers in microbiology · 2015Article
- The genomic landscape of the verrucomicrobial methanotroph Methylacidiphilum fumariolicum SolV.BMC genomics · 2014Article
- Genomic and Physiological Analysis of Carbon Storage in the Verrucomicrobial Methanotroph "Ca. Methylacidiphilum Fumariolicum" SolV.Frontiers in microbiology · 2012Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Aerobic methanotrophic bacteria can use methane as their sole energy source. The discovery of "Ca. Methylacidiphilum fumariolicum" strain SolV and other verrucomicrobial methanotrophs has revealed that the ability of bacteria to oxidize CH(4) is much more diverse than has previously been assumed in terms of ecology, phylogeny, and physiology. A remarkable characteristic of the methane-oxidizing Verrucomicrobia is their extremely acidophilic phenotype, growing even below pH 1. In this study we used RNA-Seq to analyze the metabolic regulation of "Ca. M. fumariolicum" SolV cells growing at μ(max) in batch culture or under nitrogen fixing or oxygen limited conditions in chemostats, all at pH 2. The analysis showed that two of the three pmoCAB operons each encoding particulate methane monoxygenases were differentially expressed, probably regulated by the available oxygen. The hydrogen produced during N(2) fixation is apparently recycled as demonstrated by the upregulation of the genes encoding a Ni/Fe-dependent hydrogenase. These hydrogenase genes were also upregulated under low oxygen conditions. Handling of nitrosative stress was shown by the expression of the nitric oxide reductase encoding genes norB and norC under all conditions tested, the upregulation of nitrite reductase nirK under oxygen limitation and of hydroxylamine oxidoreductase hao in the presence of ammonium. Unraveling the gene regulation of carbon and nitrogen metabolism helps to understand the underlying physiological adaptations of strain SolV in view of the harsh conditions of its natural ecosystem.
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