Evidence map›Paper›PMID 22847852›Full record

ArticleMacromolecular bioscience2012

Fabrication of nanofiber scaffolds with gradations in fiber organization and their potential applications.

Jingwei Xie, Bing Ma, Praveesuda Lorwattanapongsa Michael, Franklin D Shuler

Abstract read
In one paragraph

Article in Macromolecular bioscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Electrospun nanofiber scaffolds with gradations in fiber organization.Journal of visualized experiments : JoVE · 2015
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jingwei XieMarshall Institute for Interdisciplinary Research and Center for Diagnostic Nanosystems, Marshall University, Huntington, WV 25755, USA. xiej@marshall.edu
Bing Ma
Praveesuda Lorwattanapongsa Michael
Franklin D Shuler

Funding

Kentucky Center for Clinical and Translational ScienceUL1TR001998 · NCATS · UNIVERSITY OF KENTUCKY · PI HARTMANN, KATHERINE E, KERN, PHILIP A · 2016 to 2025
$34.2M
Kentucky Center for Clinical and Translational ScienceUL1TR000117 · NCATS · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2012 to 2015
$13.3M
KENTUCKY CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCEUL1RR033173 · NCRR · UNIVERSITY OF KENTUCKY · PI KERN, PHILIP A · 2011 to 2011
$3.5M
Combination of Nanofiber Scaffolds with Gradations in Fiber Organization and MineR15AR063901 · NIAMS · MARSHALL UNIVERSITY · PI SHULER, FRANKLIN D · 2013 to 2013
$293k
NCATS NIH HHS UL1 TR000117NCATS NIH HHS UL1 TR001998NCRR NIH HHS UL1 RR033173NCRR NIH HHS UL1RR033173NIAMS NIH HHS R15 AR063901
6 · The paper itself

Abstract

A new and simple method for fabrication of nanofiber scaffolds with gradations in fiber organization is reported. The nanofiber organization, achieved by deposition of random fibers on the uniaxially aligned nanofiber mat in a gradient manner, directed morphological changes of applied adipose-derived stem cells. These morphological changes and resultant biochemical changes can help mimic the structural orientation of complex biomechanical structures like the collagen fiber structure at the tendon-to-bone insertion site. In addition, chemical gradients can be established through nanoencapsulation in this novel scaffold allowing for enhanced biomedical applications.

Indexed as

Adipose TissueBiocompatible MaterialsBone and BonesCell DifferentiationCells, CulturedHumansMicroscopy, Electron, ScanningMicroscopy, FluorescenceNanofibersPolyestersStem CellsTissue EngineeringTissue ScaffoldsBiocompatible MaterialspolycaprolactonePolyesters

Identifiers

PMID22847852
PMCPMC3544006

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.