Evidence map›Paper›PMID 22847374›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society2012

eMouseAtlas, EMAGE, and the spatial dimension of the transcriptome.

Chris Armit, Shanmugasundaram Venkataraman, Lorna Richardson, Peter Stevenson, Julie Moss, Liz Graham, Allyson Ross, Yiya Yang, Nicholas Burton, Jianguo Rao and 5 more

Abstract read
In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. The 'straight mouse': defining anatomical axes in 3D embryo models.Database : the journal of biological databases and curation · 2017
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. eMouseAtlas informatics: embryo atlas and gene expression database.Mammalian genome : official journal of the International Mammalian Genome Society · 2015
    Article
  15. Developing the eHistology Atlas.Database : the journal of biological databases and curation · 2015
    Article
  16. Article
  17. The gene expression database for mouse development (GXD): putting developmental expression information at your fingertips.Developmental dynamics : an official publication of the American Association of Anatomists · 2014
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Chris ArmitMRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh EH4 2XU, Scotland, UK. Chris.Armit@igmm.ed.ac.uk
Shanmugasundaram Venkataraman
Lorna Richardson
Peter Stevenson
Julie Moss
Liz Graham
Allyson Ross
Yiya Yang
Nicholas Burton
Jianguo Rao
Bill Hill
Dominic Rannie
Mike Wicks
Duncan Davidson
Richard Baldock

Funding

Biotechnology and Biological Sciences Research Council RA1641Medical Research Council MC_U127527203
6 · The paper itself

Abstract

eMouseAtlas (www.emouseatlas.org) is a comprehensive online resource to visualise mouse development and investigate gene expression in the mouse embryo. We have recently deployed a completely redesigned Mouse Anatomy Atlas website (www.emouseatlas.org/emap/ema) that allows users to view 3D embryo reconstructions, delineated anatomy, and high-resolution histological sections. A new feature of the website is the IIP3D web tool that allows a user to view arbitrary sections of 3D embryo reconstructions using a web browser. This feature provides interactive access to very high-volume 3D images via a tiled pan-and-zoom style interface and circumvents the need to download large image files for visualisation. eMouseAtlas additionally includes EMAGE (Edinburgh Mouse Atlas of Gene Expression) (www.emouseatlas.org/emage), a freely available, curated online database of in situ gene expression patterns, where gene expression domains extracted from raw data images are spatially mapped into atlas embryo models. In this way, EMAGE introduces a spatial dimension to transcriptome data and allows exploration of the spatial similarity between gene expression patterns. New features of the EMAGE interface allow complex queries to be built, and users can view and compare multiple gene expression patterns. EMAGE now includes mapping of 3D gene expression domains captured using the imaging technique optical projection tomography. 3D mapping uses WlzWarp, an open-source software tool developed by eMouseAtlas.

Indexed as

Atlases as TopicTranscriptomeAnimalsMice

Identifiers

PMID22847374
PMCPMC3463796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.