Evidence map›Paper›PMID 22847274›Full record

ArticleVirus genes2012

Isolation, preliminary characterization, and full-genome analyses of tick-borne encephalitis virus from Mongolia.

Stefan Frey, Ilona Mossbrugger, Damdin Altantuul, Jigjav Battsetseg, Rendoo Davaadorj, Damdindorj Tserennorov, Tsoodol Buyanjargal, Dashdavaa Otgonbaatar, Lothar Zöller, Stephanie Speck and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Virus genes, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Stefan FreyDepartment of Virology & Rickettsiology, Bundeswehr Institute of Microbiology, Neuherbergstraße 11, Munich, Germany.
Ilona Mossbrugger
Damdin Altantuul
Jigjav Battsetseg
Rendoo Davaadorj
Damdindorj Tserennorov
Tsoodol Buyanjargal
Dashdavaa Otgonbaatar
Lothar Zöller
Stephanie Speck
Roman Wölfel
Gerhard Dobler
Sandra Essbauer
Institut für Mikrobiologie der BundeswehrNational Center for Communicable Diseases · MN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tick-borne encephalitis virus (TBEV) causes one of the most important inflammatory diseases of the central nervous system, namely severe encephalitis in Europe and Asia. Since the 1980s tick-borne encephalitis is known in Mongolia with increasing numbers of human cases reported during the last years. So far, however, data on TBEV strains are still sparse. We herein report the isolation of a TBEV strain from Ixodes persulcatus ticks collected in Mongolia in 2010. Phylogenetic analysis of the E-gene classified this isolate as Siberian subtype of TBEV. The Mongolian TBEV strain showed differences in virus titers, plaque sizes, and growth properties in two human neuronal cell-lines. In addition, the 10,242 nucleotide long open-reading frame and the corresponding polyprotein sequence were revealed. The isolate grouped in the genetic subclade of the Siberian subtype. The strain Zausaev (AF527415) and Vasilchenko (AF069066) had 97 and 94 % identity on the nucleotide level. In summary, we herein describe first detailed data regarding TBEV from Mongolia. Further investigations of TBEV in Mongolia and adjacent areas are needed to understand the intricate dispersal of this virus.

Indexed as

Genome, ViralAmino Acid SequenceAnimalsCell Line, TumorChlorocebus aethiopsEncephalitis Viruses, Tick-BorneHumansIxodesMolecular Sequence DataMongoliaOpen Reading FramesPhylogenyReal-Time Polymerase Chain ReactionVero CellsViral Envelope ProteinsViral Loadglycoprotein E, FlavivirusViral Envelope Proteins

Identifiers

PMID22847274
OpenAlexW2038047533

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.