Evidence map›Paper›PMID 22847196›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2012

Serum C-reactive protein as a possible marker to predict delayed hemorrhage after colonoscopic polypectomy.

Liangqin Wu, Tiemei Han, Xiaoyuan Fan, Wensheng Pan, Chunfu Wang, Hua Zhong, Xinbo Ai, Wanjun Zhang, Xiang Xu, Zaiyuan Ye and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Investigation of Insulin-Like Growth Factor-1 (IGF-1), P53, and Wilms' Tumor 1 (WT1) Expression Levels in the Colon Polyp Subtypes in Colon Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 2 countries.

Liangqin WuDepartment of Gastroenterology, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Tiemei Han
Xiaoyuan Fan
Wensheng Pan
Chunfu Wang
Hua Zhong
Xinbo Ai
Wanjun Zhang
Xiang Xu
Zaiyuan Ye
Takesh Terai
Nobuhiro Sato
Sumio Watanabe
Undurti N Das
Second Affiliated Hospital of Zhejiang University · CNJuntendo University · JPAir Force Medical University · CNWeifang Medical University · CNYiwu Science and Technology Research Institute · CNZhejiang Hospital · CNZhuhai People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-polypectomy hemorrhage is one of the complications of colonscopic polypectomy. And there is no definitive and convenient laboratory test that could be used to predict risk of delayed post-polypectomy hemorrhage. This research aimed to study risk prediction of delayed post-polypectomy hemorrhage using serum C-reactive protein (CRP) level as a marker. MATERIAL/

methodsIn a retrospective, case-controlled study, 302 cases of post-polypectomy patients were divided into hemorrhage group and non-hemorrhage group. The CRP levels 24-hours after colonscopic treatment were compared between the two groups to assess whether elevated serum CRP levels in addition to other risk factors such as age, gender, smoking, alcohol consumption, hypertension (AHT) and size of polyps may predict risk of delayed post-polypectomy hemorrhage.

resultsThe hemorrhage group had significantly higher levels of serum CRP (32.50±17.34 mg/L vs. 6. 32±6.02 mg/dL) and were also having a higher incidence of hypertension compared to the non- hemorrhage group (both P<0.05). Patients with elevated serum CRP levels (≥10 mg/L) after colonscopic treatment are at a higher risk of developing post-polypectomy hemorrhage (OR 1.329, 95%CI 1.125-1.571) as compared with patients whose CRP levels were not increased.

conclusionsA higher level of serum CRP may serve as an indicator of delayed post-polypectomy hemorrhage and there appears to be a direct relationship between the serum CRP levels and the risk of post-polypectomy hemorrhage: the higher CRP levels the higher the risk of post-polypectomy hemorrhage.

Indexed as

BiomarkersColonoscopyC-Reactive ProteinFemaleHemorrhageHumansIntestinal PolypsLogistic ModelsMaleMiddle AgedMultivariate AnalysisPostoperative ComplicationsRisk FactorsBiomarkersC-Reactive Protein

Identifiers

PMID22847196
PMCPMC3560690
OpenAlexW2040476364

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.