Evidence map›Paper›PMID 22846419›Full record

ArticleEnvironmental health perspectives2012

Research opportunities for cancer associated with indoor air pollution from solid-fuel combustion.

Britt C Reid, Armen A Ghazarian, David M DeMarini, Amir Sapkota, Darby Jack, Qing Lan, Deborah M Winn, Linda S Birnbaum

Abstract read
In one paragraph

Article in Environmental health perspectives, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Fuel for Life: Domestic Cooking Fuels and Women's Health in Rural China.International journal of environmental research and public health · 2016
    Article
  12. Polycyclic aromatic hydrocarbons: from metabolism to lung cancer.Toxicological sciences : an official journal of the Society of Toxicology · 2015
    Review
  13. Article
  14. Article
  15. Challenges and opportunities in international molecular cancer prevention research: An ASPO Molecular Epidemiology and the Environment and International Cancer Prevention Interest Groups Report.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2014
    Article
  16. Household Air Pollution (HAP) and Cancer: What (HAP)pens Next?Journal of pulmonary & respiratory medicine · 2014
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Britt C ReidModifiable Risk Factors Branch, Epidemiology and Genomics Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892, USA. reidbr@mail.nih.gov
Armen A Ghazarian
David M DeMarini
Amir Sapkota
Darby Jack
Qing Lan
Deborah M Winn
Linda S Birnbaum

Funding

MARYLAND POPULATION RESEARCH CENTERR24HD041041 · NICHD · UNIV OF MARYLAND, COLLEGE PARK · PI HOFFERTH, SANDRA L · 2001 to 2016
$6.6M
NICHD NIH HHS R24 HD041041
6 · The paper itself

Abstract

backgroundIndoor air pollution (IAP) derived largely from the use of solid fuels for cooking and heating affects about 3 billion people worldwide, resulting in substantial adverse health outcomes, including cancer. Women and children from developing countries are the most exposed populations. A workshop was held in Arlington, Virginia, 9-11 May 2011, to better understand women's and children's potential health effects from IAP in developing countries. Workshop participants included international scientists, manufacturers, policy and regulatory officials, community leaders, and advocates who held extensive discussions to help identify future research needs.

objectivesOur objective was to identify research opportunities regarding IAP and cancer, including research questions that could be incorporated into studies of interventions to reduce IAP exposure. In this commentary, we describe the state of the science in understanding IAP and its associations with cancer and suggest research opportunities for improving our understanding of the issues. DISCUSSION: Opportunities for research on IAP and cancer include studies of the effect of IAP on cancers other than lung cancer; studies of genetic factors that modify susceptibility; studies to determine whether the effects of IAP are mediated via germline, somatic, and/or epigenetic changes; and studies of the effects of IAP exposure via dermal and/or oral routes.

conclusionsIAP from indoor coal use increases the risk of lung cancer. Installing chimneys can reduce risk, and some genotypes, including GSTM1-null, can increase risk. Additional research is needed regarding the effects of IAP on other cancers and the effects of different types of solid fuels, oral and dermal routes of IAP exposure, genetic and epigenetic mechanisms, and genetic susceptibility.

Indexed as

Developing CountriesAir Pollution, IndoorCharcoalCoalCookingFecesGenetic Predisposition to DiseaseHeatingHumansLung NeoplasmsNeoplasmsRisk FactorsWoodCharcoalCoal

Identifiers

PMID22846419
PMCPMC3556624

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.