Trial reportJournal of the American Academy of Nurse Practitioners2012
Pilot testing of an HIV medication adherence intervention in a public clinic in the Deep South.
Trial report in Journal of the American Academy of Nurse Practitioners, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Complex solutions for a complex problem: A meta-analysis of the efficacy of multiple-behavior interventions on change in outcomes related to HIV.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2021Pooled it
- Psychosocial interventions enhance HIV medication adherence: A systematic review and meta-analysis.Journal of health psychology · 2020Pooled it
- Challenges in the Evaluation of Interventions to Improve Engagement Along the HIV Care Continuum in the United States: A Systematic Review.AIDS and behavior · 2017Pooled it
- Motivational Interviewing Improves Medication Adherence: a Systematic Review and Meta-analysis.Journal of general internal medicine · 2016Pooled it
- Identifying Best Practices for Increasing Linkage to, Retention, and Re-engagement in HIV Medical Care: Findings from a Systematic Review, 1996-2014.AIDS and behavior · 2016Pooled it
- Effects of integrated interventions on transmission risk and care continuum outcomes in persons living with HIV: meta-analysis, 1996-2014.AIDS (London, England) · 2015Pooled it
- The State of Adherence to HIV Care in Black Women.The Journal of the Association of Nurses in AIDS Care : JANACPooled it
- Uptake of an App-Based Case Management Service for HIV-Positive Men Who Have Sex With Men in China: Process Evaluation Study.Journal of medical Internet research · 2023Trial
- Improving Adherence to Care Among "Hard to Reach" HIV-Infected Patients in Argentina.AIDS and behavior · 2016Trial
- Can phone-based motivational interviewing improve medication adherence to antiplatelet medications after a coronary stent among racial minorities? A randomized trial.Journal of general internal medicine · 2015Trial
- Effects of an intervention addressing information, motivation, and behavioral skills on HIV care adherence in a southern clinic cohort.AIDS care · 2014Trial
- Addressing Health Inequities in Digital Clinical Trials: A Review of Challenges and Solutions From the Field of HIV Research.Epidemiologic reviews · 2022Review
- A small cluster randomised clinical trial to improve health outcomes among Argentine patients disengaged from HIV care.Lancet regional health. Americas · 2022Article
- Metropolitan Atlanta Community Adolescent Rapid Testing Initiative: The impact of motivational interviewing and intensive case management on the psychosocial and clinical care outcomes of adolescents and young adults with HIV.Psychotherapy (Chicago, Ill.) · 2020Article
- Adherence Connection for Counseling, Education, and Support: Research Protocol for a Proof-of-Concept Study.JMIR research protocols · 2019Article
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- Implementation and uptake of the Conexiones y Opciones en la Argentina intervention: feasibility and acceptability.AIDS care · 2016Article
- Formative Evaluation of a Text Messaging Intervention to Promote Varenicline Adherence Among Tobacco-Dependent Persons with HIV.Journal of health communication · 2015Article
- Telephone-based motivational interviewing for medication adherence: a systematic review.Translational behavioral medicine · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
purposeStrict adherence to HIV medications is critical to ensure long-term disease control, and adherence interventions that are possible in a clinic setting with limited resources are needed. DATA SOURCES: This randomized controlled pilot study tested an adherence intervention guided by the Information-Motivation-Behavioral Skills (IMB) model. The intervention included HIV education, a peer video, motivational interviewing, and attention to behavioral skills including communication with providers and adherence-enhancing devices. Dependent variables included 3-4 week adherence recall, medication refill rate, changes in IMB subscale scores, appointment attendance, and HIV-associated laboratory findings. Seventy-three individuals starting or restarting antiretroviral therapy were enrolled and 56 were randomized.
conclusionsImprovements were seen in most outcomes, with small to moderate effect sizes, but the study was not powered to show statistical significance. Threats to power included a 51% attrition rate, resulting mostly from loss to clinical care or prolonged gaps in care. IMPLICATIONS FOR PRACTICE: A telephone-based intervention to improve HIV medication adherence shows promise. Further study is needed with greater attention to retention in care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.