Evidence map›Paper›PMID 22844574›Full record

ArticleProceedings of SPIE--the International Society for Optical Engineering2012

Managing and Querying Whole Slide Images.

Fusheng Wang, Tae W Oh, Cristobal Vergara-Niedermayr, Tahsin Kurc, Joel Saltz

Abstract read
In one paragraph

Article in Proceedings of SPIE--the International Society for Optical Engineering, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Digital neuropathology of neurodegenerative disorders: Foundations, research advances, and future directions.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Distributed and parallel databases · 2019
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fusheng WangCenter for Comprehensive Informatics, Emory University, Atlanta, Georgia, USA.
Tae W Oh
Cristobal Vergara-Niedermayr
Tahsin Kurc
Joel Saltz
Emory University · USRutgers Cancer Institute of New Jersey

Funding

CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR025008 · NCRR · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2007 to 2011
$29.0M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
The CardioVascular Research GridR24HL085343 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI WINSLOW, RAIMOND LESTER · 2007 to 2015
$19.4M
Minority Health-GRID Network: A Genomics Resource for Health Disparity ResearchRC4MD005964 · NIMHD · MOREHOUSE SCHOOL OF MEDICINE · PI DAVIS, ROBERT LOWELL, NICKERSON, DEBORAH A · 2010 to 2010
$13.3M
Image Mining for Comparative Analysis of Expression Patterns in Tissue MicroarrayR01LM009239 · NLM · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI FORAN, DAVID J, SALTZ, JOEL H. · 2007 to 2016
$4.5M
Center for Grid-Enabled Medical Image AnalysisP20EB000591 · NIBIB · OHIO STATE UNIVERSITY · PI SALTZ, JOEL H · 2003 to 2005
$2.1M
Informatics for Integrative Brain Tumor Whole Slide AnalysisR01LM011119 · NLM · STATE UNIVERSITY NEW YORK STONY BROOK · PI FORAN, DAVID J, SALTZ, JOEL H. · 2011 to 2014
$1.8M
CCR NIH HHS HHSN261200800001CNCATS NIH HHS UL1 TR000454NCI NIH HHS HHSN261200800001ENCI NIH HHS N01 CO012400NCRR NIH HHS UL1 RR025008NHLBI NIH HHS R24 HL085343NIBIB NIH HHS P20 EB000591NIMHD NIH HHS RC4 MD005964NLM NIH HHS R01 LM009239NLM NIH HHS R01 LM011119
6 · The paper itself

Abstract

High-resolution pathology images provide rich information about the morphological and functional characteristics of biological systems, and are transforming the field of pathology into a new era. To facilitate the use of digital pathology imaging for biomedical research and clinical diagnosis, it is essential to manage and query both whole slide images (WSI) and analytical results generated from images, such as annotations made by humans and computed features and classifications made by computer algorithms. There are unique requirements on modeling, managing and querying whole slide images, including compatibility with standards, scalability, support of image queries at multiple granularities, and support of integrated queries between images and derived results from the images. In this paper, we present our work on developing the Pathology Image Database System (PIDB), which is a standard oriented image database to support retrieval of images, tiles, regions and analytical results, image visualization and experiment management through a unified interface and architecture. The system is deployed for managing and querying whole slide images for In Silico brain tumor studies at Emory University. PIDB is generic and open source, and can be easily used to support other biomedical research projects. It has the potential to be integrated into a Picture Archiving and Communications System (PACS) with powerful query capabilities to support pathology imaging.

Identifiers

PMID22844574
PMCPMC3405921
OpenAlexW1978874224

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.