Evidence map›Paper›PMID 22844545›Full record

ArticleCurrent cardiovascular risk reports2012

Exercise-induced Signals for Vascular Endothelial Adaptations: Implications for Cardiovascular Disease.

Nathan T Jenkins, Jeffrey S Martin, M Harold Laughlin, Jaume Padilla

Abstract read
In one paragraph

Article in Current cardiovascular risk reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Prolonged sitting leg vasculopathy: contributing factors and clinical implications.American journal of physiology. Heart and circulatory physiology · 2017
    Review
  9. Article
  10. Review
  11. Article
  12. Chronic endurance exercise affects paracrine action of CD31+ and CD34+ cells on endothelial tube formation.American journal of physiology. Heart and circulatory physiology · 2015
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Exercise: putting action into our epigenome.Sports medicine (Auckland, N.Z.) · 2014
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nathan T JenkinsBiomedical Sciences, University of Missouri, Columbia, MO.
Jeffrey S Martin
M Harold Laughlin
Jaume Padilla

Funding

TRAINING: MUSCLE BLOOD FLOW &CAPILLARY DYNAMICSR01HL036088 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI LAUGHLIN, M HAROLD · 1985 to 2013
$4.0M
Exercise &Health: Integration from Molecule to PatientT32AR048523 · NIAMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI TERJUNG, RONALD L · 2003 to 2013
$2.5M
NHLBI NIH HHS R01 HL036088NIAMS NIH HHS T32 AR048523
6 · The paper itself

Abstract

This article reviews recent advances in our understanding of hemodynamic signals, external/compressive forces, and circulating factors that mediate exercise training-induced vascular adaptations, with particular attention to the roles of these signals in prevention and treatment of endothelial dysfunction and cardiovascular (CV) diseases.

Identifiers

PMID22844545
PMCPMC3404842

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.