ArticlePloS one2012
Identification of novel markers of mouse fetal ovary development.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 49 citations in OpenAlex.
- Sertoli cells as a hub in testicular development and male reproductive.Frontiers in cell and developmental biology · 2025Review
- Implementation of the Methyl-Seq platform to identify tissue- and sex-specific DNA methylation differences in the rat epigenome.Epigenetics · 2024Article
- Long Non-Coding RNAs Differentially Expressed in Swine Fetuses.Animals : an open access journal from MDPI · 2024Article
- Gonadal Sex Differentiation and Ovarian Organogenesis along the Cortical-Medullary Axis in Mammals.International journal of molecular sciences · 2022Review
- Profiling and Functional Analysis of long non-coding RNAs in yak healthy and atretic follicles.Animal reproduction · 2022Article
- Transcriptome analysis reveals that long noncoding RNAs contribute to developmental differences between medium-sized ovarian follicles of Meishan and Duroc sows.Scientific reports · 2021Article
- Expression and possible roles of extracellular signal-related kinases 1-2 (ERK1-2) in mouse primordial germ cell development.The Journal of reproduction and development · 2020Article
- Mouse Gonad Development in the Absence of the Pro-Ovary Factor WNT4 and the Pro-Testis Factor SOX9.Cells · 2020Article
- Disorders of Sexual Development: Current Status and Progress in the Diagnostic Approach.Current urology · 2020Review
- The gene encoding the ketogenic enzyme HMGCS2 displays a unique expression during gonad development in mice.PloS one · 2020Article
- Transcriptome profiling reveals male- and female-specific gene expression pattern and novel gene candidates for the control of sex determination and gonad development in Xenopus laevis.Development genes and evolution · 2019Article
- XY oocytes of sex-reversed females with a Sry mutation deviate from the normal developmental process beyond the mitotic stage†.Biology of reproduction · 2019Article
- Polygenic and sex specific architecture for two maturation traits in farmed Atlantic salmon.BMC genomics · 2019Article
- Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries.PLoS genetics · 2018Article
- Effect of FAM196B in human lung adenocarcinoma.Journal of Cancer · 2018Article
- X chromosome inactivation in a female carrier of a 1.28 Mb deletion encompassing the human X inactivation centre.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Article
- Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary.Developmental biology · 2017Article
- Specific autoantigens identified by sera obtained from mice that are immunized with testicular germ cells alone.Scientific reports · 2016Article
- A comparison of sexing methods in fetal mice.Lab animal · 2016Article
- Geography of follicle formation in the embryonic mouse ovary impacts activation pattern during the first wave of folliculogenesis.Biology of reproduction · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 1 institution in 1 country.
Funding
Abstract
In contrast to the developing testis, molecular pathways driving fetal ovarian development have been difficult to characterise. To date no single master regulator of ovarian development has been identified that would be considered the female equivalent of Sry. Using a genomic approach we identified a number of novel protein-coding as well as non-coding genes that were detectable at higher levels in the ovary compared to testis during early mouse gonad development. We were able to cluster these ovarian genes into different temporal expression categories. Of note, Lrrc34 and AK015184 were detected in XX but not XY germ cells before the onset of sex-specific germ cell differentiation marked by entry into meiosis in an ovary and mitotic arrest in a testis. We also defined distinct spatial expression domains of somatic cell genes in the developing ovary. Our data expands the set of markers of early mouse ovary differentiation and identifies a classification of early ovarian genes, thus providing additional avenues with which to dissect this process.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.