ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2012
Moderate intensity, but not high intensity, treadmill exercise training alters power output properties in myocardium from aged rats.
Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 21 citations in OpenAlex.
- Article
- A high-whey-protein diet does not enhance mechanical and structural remodeling of cardiac muscle in response to aerobic exercise in rats.Physical activity and nutrition · 2022Article
- Consumption of a high-fat-high-sucrose diet partly diminishes mechanical and structural adaptations of cardiac muscle following resistance training.Physical activity and nutrition · 2021Article
- Interaction of genetic background and exercise training intensity on endothelial function in mouse aorta.The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology · 2020Article
- Force properties of skinned cardiac muscle following increasing volumes of aerobic exercise in rats.Journal of applied physiology (Bethesda, Md. : 1985) · 2018Article
- Effect of high-intensity exercise and high-fat diet on lipid metabolism in the liver of rats.Journal of exercise nutrition & biochemistry · 2015Article
- Effect of age and exercise on the viscoelastic properties of rat tail tendon.Annals of biomedical engineering · 2013Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Aging is characterized by a progressive decline in cardiac function, but endurance exercise training has been shown to retard a number of deleterious effects of aging. However, underlying mechanisms by which exercise training improves age-related decrements in myocardial contractile function are not well understood. The purpose of this study was to determine the effects of exercise training on power output properties in permeablized (skinned) myocytes of old rats. Thirty-month-old rats were divided into sedentary control (C) and groups undergoing 11 weeks of treadmill exercise training at moderate intensity (MI) and at high intensity (HI). Peak power output normalized to maximal force was significantly increased in MI but not in HI compared to C with significant increases in atrial myosin light chain 1 in ventricle. These results suggest that MI exercise training is beneficial as a significant increase was seen in the ability of the myocardium to do work, but this effect was not seen with HI training.
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