Evidence map›Paper›PMID 22843310›Full record

Trial reportLasers in medical science2013

Effect of low-level laser therapy after extraction of impacted lower third molars.

Maurizio Ferrante, Morena Petrini, Paolo Trentini, Giorgio Perfetti, Giuseppe Spoto

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02602431 (A Unique Application of Low Laser Therapy After Third Molar Surgery), which is not on this map. Cited by 54 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 4 pooled it
3.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02602431 naunknown statusnot on this mapstarted 2014, after this paper: background citation

A Unique Application of Low Laser Therapy After Third Molar Surgery: A Randomized Controlled Clinical Trial

TypeinterventionalSponsorUniversity of Sao PauloRan2014 to 2016Enrolled30ConditionsTrismus, Edema, PainArmsExtra-oral laser irradiation, Intra-oral laser irradiation, Extra-oral placebo, Intra-oral Placebo
3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 4 syntheses or guidelines pooled it, 178 citations in OpenAlex.

  1. Cost-Effectiveness Analysis of Photobiomodulation After Third Molar Extraction for Pain Control.International journal of environmental research and public health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Maurizio FerranteDental Materials, Department of Oral Dental Diseases, University of Chieti-Italy, Via Vestini 31, 66013, Chieti, Italy. maurizio.ferrante@gmail.com
Morena Petrini
Paolo Trentini
Giorgio Perfetti
Giuseppe Spoto
University of Chieti-Pescara · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study is to evaluate the effectiveness of the low-level laser therapy (LLLT) in the control of pain, swelling, and trismus associated with surgical removal of impacted lower third molars. Thirty patients were randomized into two treatment groups, each with 15 patients-group test (LLLT) and a group control (no-LLLT)-and were told to avoid any analgesics 12 h before the procedure. In group test, the 980-nm diode-laser (G-Laser 25 Galbiati, Italy) was applied, using a 600-μm handpiece, intraorally (lingual and vestibular) at 1 cm from the involved area and extraoral at the insertion point of the masseter muscle immediately after surgery and at 24 h. The group control received only routine management. Parameters used for LLLT were: continuous mode, at 300 mW (0.3 W) for a total of 180 s (60 s × 3) (0.3 W × 180 s=54 J). Group test showed improvement in the interincisal opening and remarkable reduction of trismus, swelling and intensity of pain on the first and the seventh postoperative days. Although LLLT has been reported to prevent swelling and trismus following the removal of impacted third molars, some of these studies reported a positive laser effect while others did not. All references to the use of laser therapy in the postoperative management of third molar surgery employ different methodologies and, in some, explanations as to selection of their respective radiation parameters are not given. This study has demonstrated that LLLT, with these parameters, is useful for the reduction of postoperative discomfort after third-molar surgery.

Indexed as

Low-Level Light TherapyTooth ExtractionAdolescentAdultEdemaFemaleHumansLasers, SemiconductorMaleMolar, ThirdPostoperative ComplicationsPostoperative PainTooth, ImpactedTrismusYoung Adult

Identifiers

PMID22843310
OpenAlexW2082534915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.