Evidence map›Paper›PMID 22843250›Full record

ArticleAIDS and behavior2013

Measurement model exploring a syndemic in emerging adult gay and bisexual men.

Perry N Halkitis, Robert W Moeller, Daniel E Siconolfi, Erik D Storholm, Todd M Solomon, Kristen L Bub

Abstract read
In one paragraph

Article in AIDS and behavior, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed, 1 pooled it
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Stimulant Use, HIV, and Plasma Metabolites Among Men.Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology · 2025
    Article
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  12. Post-Exposure Prophylaxis and Methamphetamine Use among Young Sexual Minority Men: The P18 Cohort Study.International journal of environmental research and public health · 2022
    Article
  13. Do psychosocial factors mediate sexual minorities' risky sexual behaviour? A twin study.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2022
    Article
  14. Article
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32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Perry N HalkitisCenter for Health, Identity, Behavior & Prevention Studies, The Steinhardt School of Culture, Education, and Human Development, New York University, NY 10003, USA. perry.halkitis@nyu.edu
Robert W Moeller
Daniel E Siconolfi
Erik D Storholm
Todd M Solomon
Kristen L Bub
New York University · USAuburn University · US

Funding

Syndemic Production in Emergent Adult MenR01DA025537 · NIDA · RBHS-SCHOOL OF PUBLIC HEALTH · PI HALKITIS, PERRY N · 2009 to 2018
$6.0M
NIDA NIH HHS R01 DA025537NIDA NIH HHS R01DA025537
6 · The paper itself

Abstract

The current study was designed to develop a better understanding of the nature of the relationships between mental health burden, drug use, and unprotected sexual behavior within a sample of emerging adult gay and bisexual men, ages 18-19 (N = 598) and to test a theory of syndemics using structural equation modeling. Participants were actively recruited from community-based settings and the Internet for participation in a seven-wave cohort study. Data for participant characteristics and mental health were collected via computer-assisted survey, while drug use and unprotected sex behaviors for the month prior to assessment were collected via a calendar-based technique. Using the baseline data, we developed and tested structural equation models for mental health burden, drug use, and unprotected sex and also tested a second-order model for a single syndemic. First-order measurement models for each of the three epidemics were successfully identified using observed data. Tests of a second-order model seeking to explain the three epidemics as a single syndemic fit poorly. However, a second-order construct comprised of mental health burden and drug use fit the data well and was highly associated with the first-order construct of unprotected sex. The findings advance a theory of syndemics and suggest that in order to be maximally effective both HIV prevention and HIV care must be delivered holistically such that sexual risk behaviors are addressed in relation to, and in sync with, the drug use and mental health of the individual.

Indexed as

AdolescentBisexualityCohort StudiesCondomsData Interpretation, StatisticalHealth Knowledge, Attitudes, PracticeHIV InfectionsHomosexuality, MaleHumansMaleMental HealthModels, StatisticalRisk-TakingSexual BehaviorSexual PartnersSocial Support

Identifiers

PMID22843250
PMCPMC3675898
OpenAlexW2024499267

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.