Evidence map›Paper›PMID 22843249›Full record

ReviewImmunogenetics2012

Immunogenetics of the NKG2D ligand gene family.

Masanori Kasahara, Shigeru Yoshida

Abstract readReview
PubMed Publisher
In one paragraph

Review in Immunogenetics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 36 citations in OpenAlex.

  1. Haploidentical Natural Killer Cells Infused before Allogeneic Stem Cell Transplantation for Myeloid Malignancies: A Phase I Trial.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2016
    Trial
  2. Article
  3. Article
  4. Article
  5. Frontiers in immunology · 2017
    Article
  6. Article
  7. Article
  8. Adoptive immunotherapy against ovarian cancer.Journal of ovarian research · 2016
    Review
  9. MICA SNPs and the NKG2D system in virus-induced HCC.Journal of gastroenterology · 2015
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Masanori KasaharaDepartment of Pathology, Hokkaido University Graduate School of Medicine, North-15 West-7, Sapporo 060-8638, Japan. mkasaha@med.hokudai.ac.jp
Shigeru Yoshida
Hokkaido University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NKG2D ligands (NKG2DLs) are a group of major histocompatibility complex (MHC) class I-like molecules, the expression of which is induced by cellular stresses such as infection, tumorigenesis, heat shock, tissue damage, and DNA damage. They act as a molecular danger signal alerting the immune system for infected or neoplastic cells. Mammals have two families of NKG2DL genes: the MHC-encoded MIC gene family and the ULBP gene family encoded outside the MHC region in most mammals. Rodents such as mice and rats lack the MIC family of ligands. Interestingly, some mammals have NKG2DL-like molecules named MILL that are phylogenetically related to MIC, but do not function as NKG2DLs. In this paper, we review our current knowledge of the MIC, ULBP, and MILL gene families in representative mammalian species and discuss the origin and evolution of the NKG2DL gene family.

Indexed as

Multigene FamilyAnimalsCattleFemaleHistocompatibility Antigens Class IHumansLigandsMembrane GlycoproteinsMiceNK Cell Lectin-Like Receptor Subfamily KPrimatesRatsHistocompatibility Antigens Class ILigandsMembrane GlycoproteinsMill1 protein, mouseMill2 protein, mouseNK Cell Lectin-Like Receptor Subfamily K

Identifiers

PMID22843249
OpenAlexW2094810991

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.