ArticleEuropean radiology2013
Magnetic resonance imaging findings in patients with systemic scleroderma and musculoskeletal symptoms.
Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 54 citations in OpenAlex.
- Whole-body magnetic resonance imaging in rheumatology: advancements, key applications and future perspectives.La Radiologia medica · 2026Review
- Molecular imaging of fibroblast activation in systemic sclerosis using [European journal of nuclear medicine and molecular imaging · 2026Article
- Article
- Assessment of skin fibrosis in a murine model of systemic sclerosis with multifunctional optical coherence tomography.Journal of biomedical optics · 2025Article
- Magnetic Resonance Imaging (MRI)-Based Semi-Quantitative Methods for Rheumatoid Arthritis: From Scoring to Measurement.Journal of clinical medicine · 2024Review
- Assessment of interocular symmetry of choroidal vascularity index and thickness in patients with systemic sclerosis: a prospective study.Frontiers in medicine · 2024Article
- The Involvement of Smooth Muscle, Striated Muscle, and the Myocardium in Scleroderma: A Review.International journal of molecular sciences · 2022Review
- Systemic Scleroderma-Definition, Clinical Picture and Laboratory Diagnostics.Journal of clinical medicine · 2022Review
- Using magnetic resonance imaging to map the hidden burden of muscle involvement in systemic sclerosis.Arthritis research & therapy · 2022Article
- Scleromyositis: A distinct novel entity within the systemic sclerosis and autoimmune myositis spectrum. Implications for care and pathogenesis.Frontiers in immunology · 2022Review
- Distinct MR features in scleroderma associated myopathy.La Radiologia medica · 2021Article
- Imaging in Diagnosis of Systemic Sclerosis.Journal of clinical medicine · 2021Review
- Quantitative T2 mapping accelerated by GRAPPATINI for evaluation of muscles in patients with myositis.The British journal of radiology · 2019Article
- Whole-body MRI and pathological findings in adult patients with myopathies.Skeletal radiology · 2019Review
- Review
- Fasciae of the musculoskeletal system: normal anatomy and MR patterns of involvement in autoimmune diseases.Insights into imaging · 2018Review
- Clinical Usefulness of Magnetic Resonance Imaging in Four Children With Scleroderma.Archives of rheumatology · 2018Article
- Secondary myopathy due to systemic diseases.Acta neurologica Scandinavica · 2016Review
- Whole-body MRI for full assessment and characterization of diffuse inflammatory myopathy.Acta radiologica open · 2016Article
- Whole-body MRI in adult inflammatory myopathies: Do we need imaging of the trunk?European radiology · 2015Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the role of whole-body magnetic resonance imaging (MRI) in detecting musculoskeletal involvement in patients with systemic scleroderma and musculoskeletal symptoms.
methodsEighteen consecutive patients (8 men, 10 women) with systemic scleroderma (median age 46 years) presenting with musculoskeletal complaints underwent whole-body MRI at 1.5 T. Images were evaluated for abnormal signal intensity and/or thickening of subcutaneous fatty tissue septa, muscular fasciae, intramuscular perifascial septa, muscle signal intensity and articular or tendon sheath synovial abnormalities on STIR and post-gadolinium scans. Additionally, C-reactive protein, creatinine kinase and the modified Rodnan skin score were determined.
resultsMRI indicated evidence of fasciitis, articular synovial inflammation, and subcutaneous thickening in 16 (89 %) patients. MRI findings were compatible with myopathy or myositis in 14 (78 %) patients, tenosynovitis in 11 (61 %) patients and enthesitis in 10 (56 %) patients. Typically, these manifestations were distributed symmetrically and mostly generalised. We only found few correlations with modified Rodnan skin score, C-reactive protein and creatinine kinase.
conclusionIn patients with systemic scleroderma experiencing musculoskeletal symptoms, whole-body MRI is able to detect involvement of muscles, fasciae, joints and entheses more confidently compared with clinical and laboratory parameters.
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