ArticleCancer causes & control : CCC2012
Perinatal characteristics and retinoblastoma.
Article in Cancer causes & control : CCC, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 6 of them syntheses that pooled it.
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Who cites it
45 citing papers in PubMed, 6 syntheses or guidelines pooled it, 72 citations in OpenAlex.
- Maternal infection during pregnancy and the risk of childhood cancer: a systematic review and meta-analysis.BMC medicine · 2026Pooled it
- Parental and childhood exposures and the risk of retinoblastoma, hepatoblastoma, and germ cell, bone, and soft tissue tumors in children: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Maternal Body Mass Index, Diabetes, and Gestational Weight Gain and Risk for Pediatric Cancer in Offspring: A Systematic Review and Meta-Analysis.JNCI cancer spectrum · 2022Pooled it
- Maternal Medication Use and Childhood Cancer in Offspring-Systematic Review and Considerations for Researchers.American journal of epidemiology · 2021Pooled it
- Maternal diabetes and risk of childhood malignancies in the offspring: a systematic review and meta-analysis of observational studies.Acta diabetologica · 2021Pooled it
- Cancer risk in children and young adults born preterm: A systematic review and meta-analysis.PloS one · 2019Pooled it
- HPV Infection in Children and Adolescents-A Comprehensive Review.Journal of clinical medicine · 2025Review
- Maternal illnesses during pregnancy and the risk of childhood cancer: A medical-record based analysis (UKCCS).International journal of cancer · 2025Article
- An untargeted metabolome-wide association study of maternal perinatal tobacco smoking in newborn blood spots.Metabolomics : Official journal of the Metabolomic Society · 2025Article
- Review
- Neonatal per- and polyfluoroalkyl substance exposure in relation to retinoblastoma.Environmental research · 2024Article
- The neonatal blood spot metabolome in retinoblastoma.EJC paediatric oncology · 2023Article
- Metabolite Stability in Archived Neonatal Dried Blood Spots Used for Epidemiologic Research.American journal of epidemiology · 2023Article
- The role of maternal age & birth order on the development of unilateral and bilateral retinoblastoma: a multicentre study.Eye (London, England) · 2023Article
- Maternal anemia and the risk of childhood cancer: A population-based cohort study in Taiwan.Pediatric blood & cancer · 2023Article
- Maternal anemia and childhood cancer: a population-based case-control study in Denmark.Cancer epidemiology · 2023Article
- Epidemiological aspect of retinoblastoma in the world: a review of recent advance studies.International journal of ophthalmology · 2023Review
- Maternal diabetes and childhood cancer risks in offspring: two population-based studies.British journal of cancer · 2022Article
- Human Papillomavirus Infection during Pregnancy and Childhood: A Comprehensive Review.Microorganisms · 2022Review
- Prenatal ambient pesticide exposure and childhood retinoblastoma.International journal of hygiene and environmental health · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
purposeThe etiology of retinoblastoma remains poorly understood. In the present study, we examined associations between perinatal factors and retinoblastoma risk in California children.
methodsWe identified 609 retinoblastoma cases (420 unilateral, 187 bilateral, and 2 with laterality unknown) from California Cancer Registry records of diagnoses 1988-2007 among children < 6 years of age. We randomly selected 209,051 controls from California birth rolls. The source of most study data was birth certificates. Multivariable logistic regression was used to examine associations between retinoblastoma and perinatal characteristics.
resultsBilateral retinoblastoma was associated with greater paternal age [for fathers over 35, crude odds ratio (OR) = 1.73, 95 % confidence interval (CI) 1.20, 2.47] and with twin births (OR = 1.93, 95 % CI 0.99, 3.79). Among unilateral cases, we observed an increased risk among children of US-born Hispanic mothers (OR = 1.34, 95 % CI 1.01, 1.77) while a decreased risk was observed for infants born to mothers with less than 9 years of education (OR = 0.70, 95 % CI 0.49, 1.00), a group that consisted primarily of mothers born in Mexico. We observed that maternal infection in pregnancy with any STD (OR = 3.59, 95 % CI 1.58, 8.15) was associated with bilateral retinoblastoma.
conclusionsThis study supports the findings of previous investigations reporting associations between parental age, HPV infection, and retinoblastoma.
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