ArticleJournal of Alzheimer's disease : JAD2012
The default mode network and related right hemisphere structures may be the key substrates of dementia.
Article in Journal of Alzheimer's disease : JAD, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Association of early life cardiovascular risk factors with grey matter structure in young adults in the United Kingdom: the ALSPAC study.EBioMedicine · 2024Article
- The effects of CNS atrophy and ICVD on tests of executive function and functional status are mediated by intelligence.Cerebral circulation - cognition and behavior · 2023Article
- Intelligence, cognition, and major neurocognitive disorders: From constructs to measures.Cerebral circulation - cognition and behavior · 2023Article
- Serum Adiponectin is Related to Dementia.The journals of gerontology. Series A, Biological sciences and medical sciences · 2020Article
- Changes in Brain Function Networks in Patients With Amnestic Mild Cognitive Impairment: A Resting-State fMRI Study.Frontiers in neurology · 2020Article
- Default Mode Network Lateralization and Memory in Healthy Aging and Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2018Article
- Exportation and Validation of Latent Constructs for Dementia Case Finding in a Mexican American Population-based Cohort.The journals of gerontology. Series B, Psychological sciences and social sciences · 2017Article
- δ scores predict mild cognitive impairment and Alzheimer's disease conversions from nondemented states.Alzheimer's & dementia (Amsterdam, Netherlands) · 2017Article
- Few serum proteins mediate APOE's association with dementia.PloS one · 2017Article
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- The effectiveness and unique contribution of neuropsychological tests and the δ latent phenotype in the differential diagnosis of dementia in the uniform data set.Neuropsychology · 2016Article
- Aging is a weak but relentless determinant of dementia severity.Oncotarget · 2016Article
- Spatial patterns of atrophy, hypometabolism, and amyloid deposition in Alzheimer's disease correspond to dissociable functional brain networks.Human brain mapping · 2016Article
- The Role of Alzheimer's and Cerebrovascular Pathology in Mediating the Effects of Age, Race, and Apolipoprotein E Genotype on Dementia Severity in Pathologically-Confirmed Alzheimer's Disease.Journal of Alzheimer's disease : JAD · 2016Article
- Preclinical Cerebral Network Connectivity Evidence of Deficits in Mild White Matter Lesions.Frontiers in aging neuroscience · 2016Article
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- Latent variables may be useful in pain's assessment.Health and quality of life outcomes · 2014Article
- "Executive functions" cannot be distinguished from general intelligence: two variations on a single theme within a symphony of latent variance.Frontiers in behavioral neuroscience · 2014Article
- Regional fluorodeoxyglucose metabolism and instrumental activities of daily living across the Alzheimer's disease spectrum.Journal of Alzheimer's disease : JAD · 2014Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
We have employed structural equation models to explicitly distinguish dementia-relevant variance in cognitive task performance (i.e., δ) from the variance that is unrelated to a dementing process (i.e., g'). Together g' and d comprise Spearman's "g". Although d represents only a minor fraction of the total variance in cognitive task performance, it is more strongly associated with dementia severity than is g'. In this analysis, we replicate δ in a new dataspace, the University of Kansas Brain Aging Project, and associate it specifically with regional grey matter atrophy by voxel-based morphometry of magnetic resonance imaging data. The latent variable d localizes to elements of the default mode network and related structures in the R hemisphere.
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