ArticleDento maxillo facial radiology2013
A comparison of the thresholding strategies of micro-CT for periodontal bone loss: a pilot study.
Article in Dento maxillo facial radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 41 citations in OpenAlex.
- Association between the irrigation-agitation techniques and Periapical Healing of large periapical lesions: a Randomized Controlled Trial.Clinical oral investigations · 2024Trial
- Review of image segmentation techniques for biomedical micro-CT: from laboratory absorption imaging to synchrotron phase-contrast.Npj imaging · 2026Review
- Comparison of linear and angular cephalometric measurements in CBCT using semi-automated software and artificial intelligence-generated cephalograms.BMC oral health · 2026Article
- Evaluation of Respiratory Conditions in Individuals Undergoing Rapid Maxillary Expansion: A Computational Fluid Dynamics Study.Diagnostics (Basel, Switzerland) · 2025Article
- Evaluation of the influence of hyoid bone position, volume, and types on pharyngeal airway volume and cephalometric measurements.Oral radiology · 2023Article
- Association among Orthodontic Malocclusions, Paranasal Sinuses Anatomic Variations and Adenoid Vegetation in Children Using CBCT.Children (Basel, Switzerland) · 2023Article
- Effect of different resin removal methods on enamel after metal and ceramic bracket debonding : An in vitro micro-computed tomography study.Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2022Article
- Effect of data binning and frame averaging for micro-CT image acquisition on the morphometric outcome of bone repair assessment.Scientific reports · 2022Article
- Clinically applicable artificial intelligence system for dental diagnosis with CBCT.Scientific reports · 2021Article
- Comparison of anterior mandible anatomical characteristics between obstructive sleep apnea patients and healthy individuals: a combined cone beam computed tomography and polysomnographic study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Article
- Evaluation of mallear ligaments in different voxel resolutions using cone beam computed tomography.Dento maxillo facial radiology · 2019Article
- Section Plane Effects on Morphometric Values of Microcomputed Tomography.BioMed research international · 2019Article
- Article
- Cone beam CT evaluation of mandibular molar root canal morphology in a Turkish Cypriot population.Clinical oral investigations · 2016Article
- Cone-beam CT evaluation of root canal morphology of maxillary and mandibular premolars in a Turkish Cypriot population.BDJ open · 2016Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesMicro-CT provides three-dimensional details and has been widely used for biomedical assessments. This study aimed to determine the most appropriate threshold method for quantitatively assessing the dynamics of periodontal destruction.
methodsInflammation was induced by submerging a silk ligature in the sulcus of the maxillary second molars of rats, and the animals were killed prior to ligature placement and after 7 and 21 days. The maxillae were examined for the bone resorptive activities by micro-CT, histology and tartrate-resistant acid phosphatase staining. The imaging threshold was determined by CT phantom, global and local algorithms. A bone fraction measurement from each threshold-determining technique was compared with histomorphometry. The reliability and reproducibility were examined by the intraclass correlation coefficient (ICC) and the coefficient of variation.
resultsSignificant reduction of inflammatory infiltration (p < 0.01) and active osteoclastic resorption (p < 0.05) from Day 7 to Day 21 were noted. High inter- and intraexaminer agreement were demonstrated in both histomorphometric and micro-CT assessments (ICC > 0.98). The algorithm-based technique demonstrated stronger correlation to histomorphometry than phantom-based thresholds, and the highest agreement was presented by the local algorithm (ICC > 0.96). This, however, was considerably computationally expensive.
conclusionsThe local threshold-determining algorithm is suggested for examining inflammation-induced bone loss. Further investigation will be aimed at enhancing computational efficiency.
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