ArticleEmerging infectious diseases2012
Population diversity among Bordetella pertussis isolates, United States, 1935-2009.
Article in Emerging infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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Who cites it
54 citing papers in PubMed.
- Immunological insights into why pertussis continues to be endemic.Human vaccines & immunotherapeutics · 2026Review
- Genomic epidemiology and evolution ofEmerging microbes & infections · 2025Article
- Pertussis-A Re-Emerging Threat Despite Immunization: An Analysis of Vaccine Effectiveness and Antibiotic Resistance.International journal of molecular sciences · 2025Review
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- Pertussis resurgence: epidemiological trends, pathogenic mechanisms, and preventive strategies.Frontiers in immunology · 2025Review
- Pertussis vaccines, epidemiology and evolution.Nature reviews. Microbiology · 2024Review
- Screening of Novel Drug Targets and Drug Design forCurrent research in microbial sciences · 2024Article
- Genomic dissection of the microevolution of Australian epidemicEmerging microbes & infections · 2022Article
- Evolution of Bordetella pertussis in the acellular vaccine era in Norway, 1996 to 2019.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022Article
- Pathogenicity and virulence ofVirulence · 2021Review
- Rapid and simple SNP genotyping for Bordetella pertussis epidemic strain MT27 based on a multiplexed single-base extension assay.Scientific reports · 2021Article
- Clinical characteristics, molecular epidemiology and antimicrobial susceptibility of pertussis among children in southern China.World journal of pediatrics : WJP · 2020Article
- Using big data to predict pertussis infections in Jinan city, China: a time series analysis.International journal of biometeorology · 2020Article
- Vaccine-driven virulence evolution: consequences of unbalanced reductions in mortality and transmission and implications for pertussis vaccines.Journal of the Royal Society, Interface · 2019Article
- High Prevalence of Macrolide-Resistant Bordetella pertussis and ptxP1 Genotype, Mainland China, 2014-2016.Emerging infectious diseases · 2019Article
- Association of sociodemographic factors and internet query data with pertussis infections in Shandong, China.Epidemiology and infection · 2019Article
- Resurgence of Pertussis Infections in Shandong, China: Space-Time Cluster and Trend Analysis.The American journal of tropical medicine and hygiene · 2019Article
- Role of Evolutionary Selection Acting on Vaccine Antigens in the Re-Emergence ofDiseases (Basel, Switzerland) · 2019Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since the 1980s, pertussis notifications in the United States have been increasing. To determine the types of Bordetella pertussis responsible for these increases, we divided 661 B. pertussis isolates collected in the United States during 1935-2009 into 8 periods related to the introduction of novel vaccines or changes in vaccination schedule. B. pertussis diversity was highest from 1970-1990 (94%) but declined to ≈ 70% after 1991 and has remained constant. During 2006-2009, 81.6% of the strains encoded multilocus sequence type prn2-ptxP3-ptxS1A-fim3B, and 64% were multilocus variable number tandem repeat analysis type 27. US trends were consistent with those seen internationally; emergence and predominance of the fim3B allele was the only molecular characteristic associated with the increase in pertussis notifications. Changes in the vaccine composition and schedule were not the direct selection pressures that resulted in the allele changes present in the current B. pertussis population.
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