Maintaining poise: commensal microbiota calibrate interferon responses.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

24 citing papers in PubMed.

1. Nasal microbiota clusters associate with inflammatory response, viral load, and symptom severity in experimental rhinovirus challenge.Scientific reports · 2018
   Trial
2. Type I interferons in inflammatory bowel diseases: balancing barrier integrity, repair and inflammation in the intestinal epithelium.Frontiers in medicine · 2025
   Review
3. Microbiology spectrum · 2024
   Article
4. Coprophagia in early life tunes expression of immune genes after weaning in rabbit ileum.Scientific reports · 2024
   Article
5. Gut Microbiome in Colorectal Cancer: Clinical Diagnosis and Treatment.Genomics, proteomics & bioinformatics · 2023
   Review
6. Lactobacillus rhamnosus HN001 Ameliorates BEZ235-Induced Intestinal Dysbiosis and Prolongs Cardiac Transplant Survival.Microbiology spectrum · 2022
   Article
7. Metronomic Chemotherapy in Prostate Cancer.Journal of clinical medicine · 2022
   Review
8. Infection and immunity · 2022
   Article
9. Tonic interferon restricts pathogenic IL-17-driven inflammatory disease via balancing the microbiome.eLife · 2021
   Article
10. Type I Interferons as Joint Regulators of Tumor Growth and Obesity.Cancers · 2021
    Review
11. Gut microbiota regulate tumor metastasis via circRNA/miRNA networks.Gut microbes · 2020
    Article
12. Impact of prior antibiotic use on the efficacy of nivolumab for non-small cell lung cancer.Oncology letters · 2019
    Article
13. Impact of the gut microbiota on immune checkpoint inhibitor-associated toxicities.Therapeutic advances in gastroenterology · 2019
    Review
14. MAVS deficiency induces gut dysbiotic microbiota conferring a proallergic phenotype.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
15. Microbial biomarkers for immune checkpoint blockade therapy against cancer.Journal of gastroenterology · 2018
    Review
16. Comparison of Microbiota in Patients Treated by Surgery or Chemotherapy by 16S rRNA Sequencing Reveals Potential Biomarkers for Colorectal Cancer Therapy.Frontiers in microbiology · 2018
    Article
17. The Protective Role of Type I Interferons in the Gastrointestinal Tract.Frontiers in immunology · 2017
    Review
18. Type I and III Interferon in the Gut: Tight Balance between Host Protection and Immunopathology.Frontiers in immunology · 2017
    Review
19. A Mini-Review for Cancer Immunotherapy: Molecular Understanding of PD-1/PD-L1 Pathway & Translational Blockade of Immune Checkpoints.International journal of molecular sciences · 2016
    Review
20. Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.Molecular and cellular biology · 2016
    Article

Corrections and comments

• Comment on
  Commensal bacteria calibrate the activation threshold of innate antiviral immunity.2012
• Comment on
  Priming of natural killer cells by nonmucosal mononuclear phagocytes requires instructive signals from commensal microbiota.2012

Authors and funding

2 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract