ArticleBMC genomics2012
Patterns and architecture of genomic islands in marine bacteria.
Article in BMC genomics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 42 citations in OpenAlex.
- GIPSy2: high-performance and scalable genomic island prediction software.Scientific reports · 2026Article
- The environmental adaptation of acidophilic archaea: promotion of horizontal gene transfer by genomic islands.BMC genomics · 2025Article
- Biotechnologically potential genes in a polysaccharide-degrading epibiont of the Indonesian brown algae Hydroclathrus sp.Journal, genetic engineering & biotechnology · 2023Article
- Differentiated Evolutionary Strategies of Genetic Diversification in Atlantic and Pacific Thaumarchaeal Populations.mSystems · 2022Article
- Functional characterization of HigBA toxin-antitoxin system in an Arctic bacterium, Bosea sp. PAMC 26642.Journal of microbiology (Seoul, Korea) · 2022Article
- Ecologically coherent population structure of uncultivated bacterioplankton.The ISME journal · 2021Article
- Comparative Study on A Novel Pathogen of European Seabass. Diversity ofMicroorganisms · 2019Article
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- Comparative Genomics ofFrontiers in microbiology · 2019Article
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- Genome Variation in the Model Halophilic BacteriumFrontiers in microbiology · 2018Article
- Linking pangenomes and metagenomes: thePeerJ · 2018Article
- Comparative Genomics ofFrontiers in microbiology · 2018Article
- Exploring Microdiversity in NovelFrontiers in microbiology · 2017Article
- Survey of the green picoalga Bathycoccus genomes in the global ocean.Scientific reports · 2016Article
- Why Close a Bacterial Genome? The Plasmid of Alteromonas Macleodii HOT1A3 is a Vector for Inter-Specific Transfer of a Flexible Genomic Island.Frontiers in microbiology · 2016Article
- A Model of Genome Size Evolution for Prokaryotes in Stable and Fluctuating Environments.Genome biology and evolution · 2015Article
- Marine Pseudovibrio sp. as a novel source of antimicrobials.Marine drugs · 2014Review
- Genome-wide screening of pathogenicity islands in Mycobacterium tuberculosis based on the genomic barcode visualization.Molecular biology reports · 2014Article
- Ecology of marine Bacteroidetes: a comparative genomics approach.The ISME journal · 2013Article
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGenomic Islands (GIs) have key roles since they modulate the structure and size of bacterial genomes displaying a diverse set of laterally transferred genes. Despite their importance, GIs in marine bacterial genomes have not been explored systematically to uncover possible trends and to analyze their putative ecological significance.
resultsWe carried out a comprehensive analysis of GIs in 70 selected marine bacterial genomes detected with IslandViewer to explore the distribution, patterns and functional gene content in these genomic regions. We detected 438 GIs containing a total of 8152 genes. GI number per genome was strongly and positively correlated with the total GI size. In 50% of the genomes analyzed the GIs accounted for approximately 3% of the genome length, with a maximum of 12%. Interestingly, we found transposases particularly enriched within Alphaproteobacteria GIs, and site-specific recombinases in Gammaproteobacteria GIs. We described specific Homologous Recombination GIs (HR-GIs) in several genera of marine Bacteroidetes and in Shewanella strains among others. In these HR-GIs, we recurrently found conserved genes such as the β-subunit of DNA-directed RNA polymerase, regulatory sigma factors, the elongation factor Tu and ribosomal protein genes typically associated with the core genome.
conclusionsOur results indicate that horizontal gene transfer mediated by phages, plasmids and other mobile genetic elements, and HR by site-specific recombinases play important roles in the mobility of clusters of genes between taxa and within closely related genomes, modulating the flexible pool of the genome. Our findings suggest that GIs may increase bacterial fitness under environmental changing conditions by acquiring novel foreign genes and/or modifying gene transcription and/or transduction.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.