ArticleBMC infectious diseases2012
The role of diabetes co-morbidity for tuberculosis treatment outcomes: a prospective cohort study from Mwanza, Tanzania.
Article in BMC infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.
- Association between diabetes mellitus and active tuberculosis: A systematic review and meta-analysis.PloS one · 2017Pooled it
- Is there an effect of glucose lowering treatment on incidence and prognosis of tuberculosis? A systematic review.Current diabetes reports · 2014Pooled it
- Association of Diabetes Mellitus with Presentation and Treatment Outcomes among Adult Patients with Pulmonary Tuberculosis.The American journal of tropical medicine and hygiene · 2025Article
- A comparative study of clinical outcomes and risk factors of tuberculosis in kidney transplant recipients from deceased donors.European journal of medical research · 2025Article
- Article
- Comorbidity profiles among sputum-positive tuberculosis patients in Cameroon.Frontiers in tuberculosis · 2024Article
- Who Transmits Tuberculosis to Whom: A Cross-Sectional Analysis of a Cohort Study in Lima, Peru.American journal of respiratory and critical care medicine · 2024Article
- Tackling syndemics by integrating infectious and noncommunicable diseases in health systems of low- and middle-income countries: A narrative systematic review.PLOS global public health · 2024Article
- Implementation of the WHO's collaborative framework for the management of tuberculosis and diabetes: a scoping review.BMJ open · 2021Article
- Global, regional, and national prevalence of diabetes mellitus in patients with pulmonary tuberculosis: a systematic review and meta-analysis.Diabetology & metabolic syndrome · 2021Article
- Diabetes Status and Association With Risk of Tuberculosis Among Korean Adults.JAMA network open · 2021Article
- Article
- Forecasting tuberculosis using diabetes-related google trends data.Pathogens and global health · 2020Article
- Forecasting the impact of diabetes mellitus on tuberculosis disease incidence and mortality in India.Journal of global health · 2019Article
- Availability and readiness of diabetes health facilities to manage tuberculosis in Tanzania: a path towards integrating tuberculosis-diabetes services in a high burden setting?BMC public health · 2019Article
- Analytical Exploration of Potential Pathways by which Diabetes Mellitus Impacts Tuberculosis Epidemiology.Scientific reports · 2019Article
- Is there a connection between gestational diabetes mellitus, human immunodeficiency virus infection, and tuberculosis?The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2019Review
- Coinfections and comorbidities in African health systems: At the interface of infectious and noninfectious diseases.PLoS neglected tropical diseases · 2018Review
- Prevalence of diabetes mellitus in newly diagnosed pulmonary tuberculosis in Beira, Mozambique.African health sciences · 2017Article
- Endocrine dysfunction among adult patients with tuberculosis: An African experience.Indian journal of endocrinology and metabolism · 2014Review
Corrections and comments
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Authors and funding
13 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDue to the association between diabetes and pulmonary tuberculosis (TB), diabetes may threaten the control of TB. In a prospective cohort study nested in a nutrition trial, we investigated the role of diabetes on changes in anthropometry, grip strength, and clinical parameters over a five months follow-up period.
methodsAmong pulmonary TB patients with known diabetes status, we assessed anthropometry and clinical parameters (e.g. haemoglobin) at baseline and after two and five months of TB treatment. A linear mixed-effects model (repeated measurements) was used to investigate the role of diabetes during recovery.
resultsOf 1205 TB patients, the mean (standard deviation) age was 36.6 (13.0) years, 40.9% were females, 48.9% were HIV co-infected, and 16.3% had diabetes. TB patients with diabetes co-morbidity experienced a lower weight gain at two (1.3 kg, CI95% 0.5; 2.0, p = 0.001) and five months (1.0 kg, CI95% 0.3; 1.7, p = 0.007). Similarly, the increase in the level of haemoglobin was lower among TB patients with diabetes co-morbidity after two (Δ 0.6 g/dL, CI95% 0.3; 0.9 p < 0.001) and five months (Δ 0.5 g/dL, CI95% 0.2; 0.9 p = 0.004) of TB treatment, respectively.
conclusionTB patients initiating TB treatment with diabetes co-morbidity experience delayed recovery of body mass and haemoglobin, which are important for the functional recovery from disease.
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