ArticleBMC cancer2012
Trends of population-based breast cancer survival in Germany and the US: decreasing discrepancies, but persistent survival gap of elderly patients in Germany.
Article in BMC cancer, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- CA27.29 as a tumour marker for risk evaluation and therapy monitoring in primary breast cancer patients.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2016Trial
- Long-Term Outcomes and EUSOMA Quality Indicators in a Large Single-Center Surgical Breast Cancer Cohort from North Africa.Cancers · 2026Article
- Comparison of clinicopathological and prognostic features of breast cancer patients younger than 40 years and older than 65 years.Discover oncology · 2024Article
- Breast cancer mortality in 500 000 women with early invasive breast cancer diagnosed in England, 1993-2015: population based observational cohort study.BMJ (Clinical research ed.) · 2023Observational
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- Long-term Incidence and Mortality Trends for Breast Cancer in Germany.Geburtshilfe und Frauenheilkunde · 2020Article
- The intra-tumoural stroma in patients with breast cancer increases with age.Breast cancer research and treatment · 2020Article
- Observational
- Economic modeling of risk-adapted screen-and-treat strategies in women at high risk for breast or ovarian cancer.The European journal of health economics : HEPAC : health economics in prevention and care · 2019Article
- Predicting the risk of locoregional recurrence after early breast cancer: an external validation of the Dutch INFLUENCE-nomogram with clinical cancer registry data from Germany.Journal of cancer research and clinical oncology · 2019Article
- Recent Improvement in the Long-term Survival of Breast Cancer Patients by Age and Stage in Japan.Journal of epidemiology · 2018Article
- Variation in treatment and survival of older patients with non-metastatic breast cancer in five European countries: a population-based cohort study from the EURECCA Breast Cancer Group.British journal of cancer · 2018Article
- Stanniocalcin Expression as a Predictor of Late Breast Cancer Recurrence.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2018Article
- Cost-effectiveness of different strategies to prevent breast and ovarian cancer in German women with a BRCA 1 or 2 mutation.The European journal of health economics : HEPAC : health economics in prevention and care · 2018Article
- Breast cancer survival by molecular subtype: a population-based analysis of cancer registry data.CMAJ open · 2017Article
- Cancer survival in Qidong between 1972 and 2011: A population-based analysis.Molecular and clinical oncology · 2017Article
- Incidence, mortality and survival of female breast cancer during 2003-2011 in Jiangsu province, China.Chinese journal of cancer research = Chung-kuo yen cheng yen chiu · 2016Article
- The Treatment of Primary Breast Cancer in Older Women With Adjuvant Therapy: A Retrospective Analysis of Data From Over 3000 Patients From the PATH Biobank, With Two-Year Follow-up.Deutsches Arzteblatt international · 2015Article
- Convergence with SEER database achieved by a breast cancer network: a longitudinal benchmark of 5-year relative survival.Journal of cancer research and clinical oncology · 2015Article
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Abstract
backgroundStudies have revealed both higher cancer survival in the US than in Germany and substantial improvement of cancer survival in the past in these countries. This population-based study aims at comparing most recent 5-year relative survival of breast cancer patients and preceding trends in both countries.
methodsWomen with a first invasive breast cancer diagnosed and followed up between 1988 and 2008 from Germany and the US (utilizing data from the Saarland Cancer Registry and the Surveillance, Epidemiology, and End Results Program, respectively) were included. Period analysis was used to derive most up-to-date 5-year relative survival and preceding survival trends according to age and stage.
resultsSince 1993, age standardized relative survival has steadily improved in Germany and the US to 83% and 88%, respectively. In the period 2005-08, relative survival of localized cancer was above 97% in both countries, and 79% and 83% for locally/regionally spread breast cancer, respectively. Prognosis of metastasized disease has remained very poor overall, with improvement essentially being restricted to younger patients. The proportion of patients diagnosed with localized breast cancer was consistently higher in the US. If adjusted for stage, the differences in relative survival between both countries diminished over time and eventually disappeared.
conclusionsSimilar survival is now observed in both countries for patients below the age of 70 years, but in Germany survival is still much lower for elderly patients. The observed trends point to treatment advances as a major cause for improved survival. However, substantial differences in mammography usage existed between both countries and might probably also account for the observed differences (to a lesser extent, also differences in health care systems, and delivery of cancer care). Encouraging, survival of breast cancer patients has improved in Germany to a much greater extent than in the US, albeit the persisting survival gap for elderly patients in Germany requires particular attention by researchers, public health authorities, and clinicians.
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