Evidence map›Paper›PMID 22837803›Full record

ArticleInternational journal of clinical and experimental medicine2012

Early-onset breast disease: case of a Grave condition with a favorable prognosis.

James E Siegler, Steven D Jones, Emad Kandil

Open access · greenAbstract readCase Reports
In one paragraph

Article in International journal of clinical and experimental medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 99% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

James E Siegler
Steven D Jones
Emad Kandil

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between thyroid and breast diseases has been well documented, but the clinical impact of Graves' disease on breast tissue is not clear. PATIENT

findingsTwenty-seven year-old African American female patient who presented with multiple bilateral breast masses and skin thickening and ulcerations. Biopsy of the breast masses demonstrated fat necrosis. During her initial evaluation, she was found to be hyperthyroid and was ultimately diagnosed with Graves' disease. Her abnormal breast changes resolved within several months of her medical treatment for Graves' disease. SUMMARY: Graves' disease may present with acute-onset breast changes without personal history of trauma or family history of breast abnormalities.

conclusionsInteractions between thyroid and estrogen hormones should be studied further to determine their exact clinical and pathologic implications. Medical or surgical management of Graves' disease may reverse associated pathologic breast changes.

Indexed as

estrogenfat necrosisGraves’ diseasethyroid hormone

Identifiers

PMID22837803
PMCPMC3403549
OpenAlexW116091235

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.