ArticleJournal of neuro-oncology2012
The influence of surgery on quality of life in patients with intracranial meningiomas: a prospective study.
Article in Journal of neuro-oncology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Health-related quality-of-life outcomes in CNS WHO grade 2 and 3 meningioma: a systematic review.Neurosurgical review · 2025Pooled it
- Impaired health-related quality of life in meningioma patients-a systematic review.Neuro-oncology · 2017Pooled it
- FEBAIR microsurgical principles in meningiomas and recurrence: a long-term follow-up series.Frontiers in oncology · 2026Article
- Giant Meningiomas Invading the Cavernous Sinus: The "Inevitable Ones".Journal of neurological surgery. Part B, Skull base · 2025Article
- Evaluating the effects of surgery on health-related quality of life in asymptomatic meningioma patients.Neuro-oncology practice · 2025Article
- Health-related quality of life in surgically treated asymptomatic meningioma patients: A population-based matched cohort study.Neuro-oncology practice · 2024Article
- Quality of life in patients with skull base meningiomas treated with microsurgery: a prospective observational study.Acta neurochirurgica · 2024Observational
- Surgical treatment of meningiomas improves neurocognitive functioning and quality of life - a prospective single-center study.Acta neurochirurgica · 2024Article
- Meningioma: International Consortium on Meningiomas consensus review on scientific advances and treatment paradigms for clinicians, researchers, and patients.Neuro-oncology · 2024Review
- Incidence, management, and outcome of incidental meningioma: what has happened in 10 years?Journal of neuro-oncology · 2023Article
- Review
- Meningiomas with CNS invasion.Frontiers in neuroscience · 2023Review
- Health-Related Quality of Life in Intracranial Meningioma: Current Evidence and Future Directions.Advances in experimental medicine and biology · 2023Article
- Healthcare utilization and costs among intracranial meningioma patients during long-term follow-up.Journal of neuro-oncology · 2023Article
- Quality of life outcomes in incidental and operated meningiomas (QUALMS): a cross-sectional cohort study.Journal of neuro-oncology · 2023Article
- Matched case-control analysis of outcomes following surgical resection of incidental meningioma.Journal of neuro-oncology · 2022Article
- Article
- Anxiety and depression in patients with intracranial meningioma: a mixed methods analysis.BMC psychology · 2022Article
- Impact of meningioma surgery on use of antiepileptic, antidepressant, and sedative drugs: A Swedish nationwide matched cohort study.Cancer medicine · 2021Article
- Meningiomas and Cognitive Impairment after Treatment: A Systematic and Narrative Review.Cancers · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Meningiomas may influence both survival and neurological functions. Studies assessing the impact of surgery on health-related quality of life (HRQL) remain absent. In this prospective study we aimed to describe HRQL dynamics before and after surgery in patients with meningiomas. HRQL assessments were performed using EuroQol-5D (EQ-5D), a generic HRQL instrument. All adult patients with suspected intracranial meningioma from 2007 through 2011 were eligible for inclusion, and 54 patients were included after informed consent. All patients received a histopathological diagnosis of meningioma. The average preoperative EQ-5D index value (±SD) was 0.69 ± 0.26. The mean improvement 6 weeks after surgery was 0.06 (95 % CI, -0.03 to 0.16; p = 0.161) and the mean long term improvement was 0.09 (95 % CI, 0.00-0.17; p = 0.040). Surgery reduced pain/discomfort and anxiety/depression and improved the capability of performing usual activities. Clinically significant improvement at long-term assessment was noted in 25 patients (49 %) while a significant deterioration was reported in 10 patients (20 %). Patients who reported postoperative worsening of HRQL were also reporting better preoperative scores, suggesting a possible ceiling effect of EQ-5D in some of these patients. In our patients a modest average improvement in HRQL was seen after surgery for meningioma. About half of the patients reported a clinical important improvement at the late follow-up assessment. This improvement was mainly observed in the domains usual activities, pain/discomfort and anxiety/depression. However, one in five patients fared worse on late follow-up assessment, a figure of particular importance when treating asymptomatic meningiomas.
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Registered trials
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