Evidence map›Paper›PMID 22835849›Full record

ArticleJournal of affective disorders2013

Antisocial personality disorder and borderline symptoms are differentially related to impulsivity and course of illness in bipolar disorder.

Alan C Swann, Marijn Lijffijt, Scott D Lane, Joel L Steinberg, F Gerard Moeller

Open access · greenAbstract read
In one paragraph

Article in Journal of affective disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
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  6. Article
  7. Role of calcium channels in bipolar disorder.Current psychopharmacology · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Alan C SwannDepartment of Psychiatry and Behavioral Sciences, University of Texas Health Science Center, Houston, TX, USA. Alan.C.Swann@uth.tmc.edu
Marijn Lijffijt
Scott D Lane
Joel L Steinberg
F Gerard Moeller
The University of Texas Health Science Center at Houston · US

Funding

U OF TEXAS HLTH SCI CTR HOUSTON CENTER FOR CLINICAL AND TRANSLATIONAL SCIENCESUL1RR024148 · NCRR · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MCPHERSON, DAVID D · 2006 to 2010
$27.9M
Norepinephrine and ImpulsivityR01MH069944 · NIMH · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI SWANN, ALAN C · 2005 to 2009
$1.5M
Serotonin, Impulsivity, and Substance AbuseK02DA000403 · NIDA · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI MOELLER, FREDERICK GERARD · 2000 to 2011
$1.2M
NCRR NIH HHS UL1 RR024148NCRR NIH HHS UL1-RR024148NIDA NIH HHS K02 DA000403NIDA NIH HHS KO2-DA00403NIMH NIH HHS R01 MH069944NIMH NIH HHS R01-MH69944
6 · The paper itself

Abstract

backgroundInteractions between characteristics of bipolar and Axis II cluster B disorders are clinically and diagnostically challenging. Characteristics associated with personality disorders may be dimensional aspects of bipolar disorder. We investigated relationships among antisocial personality disorder (ASPD) or borderline personality disorder symptoms, impulsivity, and course of illness in bipolar disorder.

methodsSubjects with bipolar disorder were recruited from the community. Diagnosis was by structured clinical interview for DSM-IV (SCID-I and -II), psychiatric symptom assessment by the change version of the schedule for affective disorders and schizophrenia (SADS-C), severity of Axis II symptoms by ASPD and borderline personality disorder SCID-II symptoms, and impulsivity by the Barratt impulsiveness scale (BIS-11).

resultsASPD and borderline symptoms were not related to clinical state or affective symptoms. Borderline symptoms correlated with BIS-11 impulsivity scores, and predicted history of suicide attempts independently of the relationship to impulsivity. ASPD symptoms were more strongly related to course of illness, including early onset, frequent episodes, and substance-related disorders. These effects persisted after allowance for gender and substance-use disorder history.

conclusionsPersonality disorder symptoms appear to be dimensional, trait-like characteristics of bipolar disorder. ASPD and Borderline symptoms are differentially related to impulsivity and course of illness.

Indexed as

AdultAffective SymptomsAge of OnsetAntisocial Personality DisorderBipolar DisorderBorderline Personality DisorderDiagnosis, DifferentialDiagnostic and Statistical Manual of Mental DisordersFemaleHumansImpulsive BehaviorMaleMiddle AgedPsychiatric Status Rating ScalesRetrospective StudiesSubstance-Related Disorders

Identifiers

PMID22835849
PMCPMC3484175
OpenAlexW2072658826

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.