Evidence map›Paper›PMID 22835534›Full record

ReviewDental clinics of North America2012

Stem cell and biomaterials research in dental tissue engineering and regeneration.

Orapin V Horst, Miquella G Chavez, Andrew H Jheon, Tejal Desai, Ophir D Klein

Abstract readReview
In one paragraph

Review in Dental clinics of North America, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Trial
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  5. Article
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  9. Article
  10. Review
  11. Article
  12. Injectable Biomaterials for Dental Tissue Regeneration.International journal of molecular sciences · 2020
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Three-dimensional printing for craniomaxillofacial regeneration.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2017
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Orapin V HorstDivision of Endodontics, Department of Preventive and Restorative Dental Sciences, University of California, San Francisco, CA 94143-0758, USA.
Miquella G Chavez
Andrew H Jheon
Tejal Desai
Ophir D Klein

Funding

UCSF IRACDA Scholars ProgramK12GM081266 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Raymond M. Esquerra, HOLLY A. INGRAHAM · 2007 to 2026
$19.4M
An evolutionary-developmental approach to stem cells using teeth as a modelDP2OD007191 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KLEIN, OPHIR D · 2010 to 2010
$2.3M
The role of Bmi1 in regulation of dental stem cellsR01DE021420 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KLEIN, OPHIR D · 2011 to 2015
$2.0M
Modeling Dentin by G Protein Coupled Receptor SignalingK08DE022377 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HORST, ORAPIN V · 2011 to 2015
$664k
The Role of microRNAs in Tooth Regeneration using the Mouse Incisor ModelR21DE019958 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI KLEIN, OPHIR D · 2009 to 2010
$423k
NIDCR Dentist Scientist K99;Function and Regulation of Perp in AmelogenesisK99DE022059 · NIDCR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JHEON, ANDREW H. · 2011 to 2012
$255k
NIDCR NIH HHS K08 DE022377NIDCR NIH HHS K99 DE022059NIDCR NIH HHS R01 DE021420NIDCR NIH HHS R21 DE019958NIGMS NIH HHS K12 GM081266NIH HHS DP2 OD007191
6 · The paper itself

Abstract

This review summarizes approaches used in tissue engineering and regenerative medicine, with a focus on dental applications. Dental caries and periodontal disease are the most common diseases resulting in tissue loss. To replace or regenerate new tissues, various sources of stem cells have been identified such as somatic stem cells from teeth and peridontium. Advances in biomaterial sciences including microfabrication, self-assembled biomimetic peptides, and 3-dimensional printing hold great promise for whole-organ or partial tissue regeneration to replace teeth and periodontium.

Indexed as

Stem Cell TransplantationTissue ScaffoldsBiocompatible MaterialsDental CariesGuided Tissue Regeneration, PeriodontalHumansPeriodontitisPeriodontiumStem CellsToothBiocompatible Materials

Identifiers

PMID22835534
PMCPMC3494412

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.