ArticleJournal of pain and symptom management2013
Self-reported constipation in patients with advanced cancer: a preliminary report.
Article in Journal of pain and symptom management, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 46 citations in OpenAlex.
- Pilot randomized trial of an electronic symptom monitoring intervention for hospitalized patients with cancer.Annals of oncology : official journal of the European Society for Medical Oncology · 2019Trial
- Opioid-induced constipation in internal medicine: recognition and management pathways.Internal and emergency medicine · 2025Review
- Improving Diagnosis and Management of Opioid-Induced Constipation (OIC) in Clinical Practice: An Italian Expert Opinion.Journal of clinical medicine · 2024Article
- A Critical Analysis of Intestinal Enteric Neuron Loss and Constipation in Parkinson's Disease.Journal of Parkinson's disease · 2022Review
- Constipation in Chemotherapy Patients: A Diagnostic Accuracy Study.Asian Pacific journal of cancer prevention : APJCP · 2021Article
- Rates of appropriate laxative prophylaxis for opioid-induced constipation in veterans with lung cancer: a retrospective cohort study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Observational
- More opioids, more constipation? Evaluation of longitudinal total oral opioid consumption and self-reported constipation in patients with cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020Article
- Potentially Avoidable Hospital Readmissions in Patients With Advanced Cancer.Journal of oncology practice · 2019Article
- Article
- Predictors of Posthospital Transitions of Care in Patients With Advanced Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2018Article
- Article
- Managing Constipation in Adults With Cancer.Journal of the advanced practitioner in oncology · 2017Review
- Constipation in specialized palliative care: factors related to constipation when applying different definitions.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016Article
- Diagnostic Performance of Self-Assessment for Constipation in Patients With Long-Term Opioid Treatment.Medicine · 2015Observational
- Predictors of response to palliative care intervention for chronic nausea in advanced cancer outpatients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2013Article
- Assessment of Constipation in Patients With Cancer.Journal of the advanced practitioner in oncologyReview
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
contextConstipation is often inadequately assessed and underdiagnosed in patients with advanced cancer. Many studies use patient-reported constipation (PRC) as an outcome.
objectivesThe aim was to compare the accuracy of PRC as compared with the modified Rome III (ROME) criteria and to determine the agreement between PRC, physician assessment of constipation, and objective assessment of constipation by modified ROME criteria among outpatients with advanced cancer.
methodsPatients with advanced cancer attending a supportive care clinic were screened. Constipation was assessed using the modified ROME criteria, patient report (yes or no and rated 0-10; 10=worst possible symptom), and physician assessments (yes or no and rated 0-10).
resultsOne hundred patients were enrolled, and 50 of 100 patients (50%) met the modified ROME criteria for constipation. Disagreement between ROME criteria and the patient report (yes/no) was found in 33 patients (33%) and between ROME criteria and the physician assessment (yes/no) in 39 patients (39%). The best combination of sensitivity (0.84) and specificity (0.62) was found with scores ≥3/10 for PRC.
conclusionWe found a high frequency of constipation. The limited agreement with modified ROME criteria suggests that a patient's self-report as yes or no is not useful for clinical practice. Patient self-rating on a 0 to 10 scale (score of three or greater) seems to be the best tool for constipation screening among this population. More research is needed to identify the best way to assess constipation in patients with advanced cancer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.