ArticleAnnals of epidemiology2012
Depressed mood and cause-specific mortality: a 40-year general community assessment.
Article in Annals of epidemiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Depression and anxiety in relation to cancer incidence and mortality: a systematic review and meta-analysis of cohort studies.Molecular psychiatry · 2020Pooled it
- Mental Stress-Induced-Myocardial Ischemia in Young Patients With Recent Myocardial Infarction: Sex Differences and Mechanisms.Circulation · 2018Trial
- Association between solar radiation and mood disorders among Gulf Coast residents.Journal of exposure science & environmental epidemiology · 2025Article
- Depression and Coronary Artery Disease-Where We Stand?Journal of clinical medicine · 2025Review
- High Frequency of Depression in Advanced Cancer with Concomitant Comorbidities: A Registry Study.Cancers · 2025Article
- Stress and cardiovascular disease: an update.Nature reviews. Cardiology · 2024Review
- Cancer mortality in Common Mental Disorders: A 10-year retrospective cohort study.Social psychiatry and psychiatric epidemiology · 2023Article
- Gender Disparities Between Neighborhood Social Vulnerability and Psychological Distress Among Patients with Heart Disease.Journal of women's health (2002) · 2022Article
- Genetic risk for major depressive disorder and loneliness in sex-specific associations with coronary artery disease.Molecular psychiatry · 2021Article
- Depression and Endothelial Dysfunction in Psoriatic Arthritis: Is There Any Possible Relationship?Frontiers in medicine · 2021Article
- Article
- Summary of Updated Recommendations for Primary Prevention of Cardiovascular Disease in Women: JACC State-of-the-Art Review.Journal of the American College of Cardiology · 2020 · on this mapReview
- Depression and coronary heart disease: 2018 position paper of the ESC working group on coronary pathophysiology and microcirculation.European heart journal · 2020Article
- Depression and cause-specific mortality in an ethnically diverse cohort from the UK: 8-year prospective study.Psychological medicine · 2019Article
- Sex differences and the prognosis of depressive and nondepressive patients with cardiovascular risk factors: the Japan Morning Surge-Home Blood Pressure (J-HOP) study.Hypertension research : official journal of the Japanese Society of Hypertension · 2018Article
- Psychological Factors and Their Association with Ideal Cardiovascular Health Among Women and Men.Journal of women's health (2002) · 2018Article
- Association between Healthcare Utilization and Depression in Korean Women with Cardiovascular Conditions.Psychiatry investigation · 2017Article
- Sex differences in cardiovascular disease - Impact on care and outcomes.Frontiers in neuroendocrinology · 2017Review
- Behavioral, emotional and neurobiological determinants of coronary heart disease risk in women.Neuroscience and biobehavioral reviews · 2017Review
- Sex Differences in Mental Stress-Induced Myocardial Ischemia in Patients With Coronary Heart Disease.Journal of the American Heart Association · 2016Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
purposeThe current study describes how the excess mortality risk associated with depression translates into specific causes of death occurring during a 40-year follow-up period, with focus on deaths related to injuries, cardiovascular diseases, and cancer.
methodsData come from a cross-sectional survey (Community Mental Health Epidemiology Study) conducted in the early 1970s in Washington County, Maryland. Random sampling for the survey resulted in 2762 interviews. For the current analyses, baseline depressed mood was linked to current participant vital status through the use of death certificates.
resultsThe relative subdistribution hazards for cardiovascular deaths (3.08 [1.74-5.45]) and fatal injuries (4.63 [1.76-12.18]) were significant during the entire 40-year period for young adults (18-39 years old at baseline). The relative subdistribution hazard for cardiovascular deaths during the first 15 years of follow-up was pronounced in elderly (≥ 65 years) males (2.99 [1.67-5.37]) subjects. There were no significant associations between depressed mood and cancer deaths.
conclusionsIndividuals in the general community with depressed mood may be at increased risk of deaths as the result of cardiovascular disease and injury, even several decades after exposure assessment. Young adults with depressed mood appear to be particularly vulnerable to these associations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.