Evidence map›Paper›PMID 22834196›Full record

ReviewTherapeutic delivery2012

The shape of things to come: importance of design in nanotechnology for drug delivery.

Yaling Liu, Jifu Tan, Antony Thomas, Daniel Ou-Yang, Vladimir R Muzykantov

Abstract readReview
In one paragraph

Review in Therapeutic delivery, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed.

  1. CRISPR/Cas9-based nanodelivery systems for precision gene editing in neuroinflammation.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Review
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  13. Gold Nanoparticles for Wound Healing in Animal Models.Nanomaterials (Basel, Switzerland) · 2025
    Review
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  18. Article
  19. Green Synthesis of Metal Nanoparticles UsingNanotechnology, science and applications · 2025
    Review
  20. Review

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yaling LiuDepartment of Mechanical Engineering & Mechanics, Lehigh, University, Bethlehem, PA 18015, USA. yal310@lehigh.edu
Jifu Tan
Antony Thomas
Daniel Ou-Yang
Vladimir R Muzykantov

Funding

Modeling Particle Shape Effect in NanomedicineR03EB009786 · NIBIB · UNIVERSITY OF TEXAS ARLINGTON · PI LIU, YALING · 2009 to 2010
$144k
NIBIB NIH HHS EB009786NIBIB NIH HHS R03 EB009786
6 · The paper itself

Abstract

The design of nanoparticle (NP) size, shape and surface chemistry has a significant impact on their performance. While the influences of the particle size and surface chemistry on drug delivery have been studied extensively, little is known about the effect of particle shapes on nanomedicine. In this perspective article, we discuss recent progress on the design and fabrication of NPs of various shapes and their unique delivery properties. The shapes of these drug carriers play an important role in therapeutic delivery processes, such as particle adhesion, distribution and cell internalization. We envision that stimuli-responsive NPs, which actively change their shapes and other properties, might pave way to the next generation of nanomedicine.

Indexed as

Drug CarriersNanoparticlesNanotechnologyAnimalsChemistry, PharmaceuticalDelayed-Action PreparationsDrug Administration RoutesHumansParticle SizeSurface PropertiesTechnology, PharmaceuticalDelayed-Action PreparationsDrug Carriers

Identifiers

PMID22834196
PMCPMC3408634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.