ArticleParasitology research2012
Essential oil components from Asarum sieboldii Miquel are toxic to the house dust mite Dermatophagoides farinae.
Article in Parasitology research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 21 citations in OpenAlex.
- Effectiveness of Inhalation of a New Essential Oil Formulation on Asthma Through Network Pharmacology and In Vivo Analysis.Food science & nutrition · 2025Article
- Article
- Comparative Biochemical and Pharmacodynamic Analyses ofPharmaceuticals (Basel, Switzerland) · 2024Article
- Chemical Composition and Biological Activities of Essential Oils of FourMolecules (Basel, Switzerland) · 2023Article
- Exploring the Potential Effects and Mechanisms ofPharmaceutics · 2022Article
- Physiological, Biochemical and Transcriptomic Analysis of the Aerial Parts (Leaf-Blade and Petiole) ofInternational journal of molecular sciences · 2021Article
- Comparative Transcriptomic Analysis Reveals the Effects of Drought on the Biosynthesis of Methyleugenol inBiomolecules · 2021Article
- Pharmacokinetic Study of Safrole and Methyl Eugenol after Oral Administration of the Essential Oil Extracts ofBioMed research international · 2021Article
- Fumigant Toxicity and Oviposition Deterrent Activity of Volatile Constituents from Asari Radix et Rhizoma against Phthorimaea operculella (Lepidoptera: Gelechiidae).Journal of insect science (Online) · 2020Article
- Protective effect of Asarum sieboldii essential oil on ovalbumin induced allergic rhinitis in rat.Bioscience reports · 2020Article
- Asatone and Isoasatone A AgainstMolecules (Basel, Switzerland) · 2019Article
- Comparative Transcriptomics Analysis for Gene Mining and Identification of a Cinnamyl Alcohol Dehydrogenase Involved in Methyleugenol Biosynthesis fromMolecules (Basel, Switzerland) · 2018Article
- New Contributions to Asarum Powder on Immunology Related Toxicity Effects in Lung.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Environmental assessment and exposure control of dust mites: a practice parameter.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2013Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In our effort to develop novel plant-derived acaricides, we examined the contact and fumigant toxicity of Asarum heterotropoides (Asarum sieboldii Miquel) essential oil constituents to the house dust mite Dermatophagoides farinae (Acari: Pyroglyphidae). Ten constituents, including methyl eugenol (relative amount 42.18 %), were identified by gas chromatography-mass spectroscopy (GC-MS) in the A. sieboldii Miq. essential oil. In contact toxicity tests, methyl eugenol (4.2 μg/cm(2), 24 h LD50) was most toxic to D. farinae, followed by benzyl benzoate (9.1 μg/cm(2)), A. sieboldii Miq. essential oil (37.7 μg/cm(2)), and dibutyl phthalate (DBP 57.9 μg/cm(2)). The potency of methyl eugenol and A. sieboldii Miq. essential oil was higher than benzyl benzoate and DBP, with mortalities of 100, 100, 94.6, and 13.2 %, respectively, after 2.5 h of exposure. In the vapor phase mortality bioassay, methyl eugenol and A. sieboldii Miq. essential oil resulted in 100 % mortality in closed containers after 24-h exposure, but only 4.7 and 7.9 %, respectively, in open containers, indicating that the toxicity in these tests was largely due to the vapor phase. Methyl eugenol and A. sieboldii Miq. essential oil merit further study as potential D. farinae control compounds.
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