ArticleJournal of digital imaging2013
UMMPerfusion: an open source software tool towards quantitative MRI perfusion analysis in clinical routine.
Article in Journal of digital imaging, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- MR Spectroscopic Imaging of Hyperpolarized 129-Xenon in the Dissolved-Phase to Determine Regional Chemical Shifts of Hyperoxia in Healthy Porcine Lungs.NMR in biomedicine · 2025Article
- A groupwise multiresolution network for DCE-MRI image registration.Scientific reports · 2025Article
- Article
- Long-term evaluation of uterine fibroid embolisation using MRI perfusion parameters and patient questionnaires: preliminary results.BMC medical imaging · 2022Article
- A Simultaneous MultiparametricCancers · 2022Article
- AI-enhanced simultaneous multiparametricEuropean journal of nuclear medicine and molecular imaging · 2022Article
- Analysis Protocol for Dynamic Contrast Enhanced (DCE) MRI of Renal Perfusion and Filtration.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Dynamic Contrast Enhanced (DCE) MRI-Derived Renal Perfusion and Filtration: Experimental Protocol.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Sex Differences in Kidney Function and Metabolism Assessed Using Hyperpolarized [1-Tomography (Ann Arbor, Mich.) · 2020Article
- Altered Regional Cerebral Blood Flow Associated with Mood and Sleep in Shift Workers: Cerebral Perfusion Magnetic Resonance Imaging Study.Journal of clinical neurology (Seoul, Korea) · 2019Article
- Impact of the Number of Iterations in Compressed Sensing Reconstruction on Ultrafast Dynamic Contrast-enhanced Breast MR Imaging.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2019Article
- MITK-ModelFit: A generic open-source framework for model fits and their exploration in medical imaging - design, implementation and application on the example of DCE-MRI.BMC bioinformatics · 2019Article
- A modified two-compartment model for measurement of renal function using dynamic contrast-enhanced computed tomography.PloS one · 2019Observational
- The impact of injector-based contrast agent administration in time-resolved MRA.European radiology · 2018Article
- Hyperpolarized [1-Scientific reports · 2017Article
- Comparison of perfusion models for quantitative T1 weighted DCE-MRI of rectal cancer.Scientific reports · 2017Article
- Can HyperpolarizedTomography (Ann Arbor, Mich.) · 2017Article
- Comprehensive Multi-Dimensional MRI for the Simultaneous Assessment of Cardiopulmonary Anatomy and Physiology.Scientific reports · 2017Article
- Color-coded visualization of magnetic resonance imaging multiparametric maps.Scientific reports · 2017Article
- Region of interest-based versus whole-lung segmentation-based approach for MR lung perfusion quantification in 2-year-old children after congenital diaphragmatic hernia repair.European radiology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To develop a generic Open Source MRI perfusion analysis tool for quantitative parameter mapping to be used in a clinical workflow and methods for quality management of perfusion data. We implemented a classic, pixel-by-pixel deconvolution approach to quantify T1-weighted contrast-enhanced dynamic MR imaging (DCE-MRI) perfusion data as an OsiriX plug-in. It features parallel computing capabilities and an automated reporting scheme for quality management. Furthermore, by our implementation design, it could be easily extendable to other perfusion algorithms. Obtained results are saved as DICOM objects and directly added to the patient study. The plug-in was evaluated on ten MR perfusion data sets of the prostate and a calibration data set by comparing obtained parametric maps (plasma flow, volume of distribution, and mean transit time) to a widely used reference implementation in IDL. For all data, parametric maps could be calculated and the plug-in worked correctly and stable. On average, a deviation of 0.032 ± 0.02 ml/100 ml/min for the plasma flow, 0.004 ± 0.0007 ml/100 ml for the volume of distribution, and 0.037 ± 0.03 s for the mean transit time between our implementation and a reference implementation was observed. By using computer hardware with eight CPU cores, calculation time could be reduced by a factor of 2.5. We developed successfully an Open Source OsiriX plug-in for T1-DCE-MRI perfusion analysis in a routine quality managed clinical environment. Using model-free deconvolution, it allows for perfusion analysis in various clinical applications. By our plug-in, information about measured physiological processes can be obtained and transferred into clinical practice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.